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Interactions médicamenteuses

Darunavir + Miglitol

Gravité: Modérée

Darunavir and Miglitol: moderate interaction.

Dernière mise à jour

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Résumé

Darunavir, usually boosted with ritonavir or cobicistat, may be associated with insulin resistance and hyperglycemia. This could reduce the glycemic benefit of miglitol.

Ce que signifie cette interaction, en termes simples

Darunavir and Miglitol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Darunavir belongs to Anti Virals; Miglitol belongs to Endocrine.

Niveau de preuve: Low

Pourquoi elle survient

Pharmacodynamic antagonism through protease inhibitor-related insulin resistance.

Conduite à tenir

Monitor blood glucose and HbA1c after starting darunavir. Adjust antidiabetic therapy as needed.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Darunavir with Miglitol?

MediHelp rates the interaction as moderate. Darunavir and Miglitol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Darunavir, usually boosted with ritonavir or cobicistat, may be associated with insulin resistance and hyperglycemia. This could reduce the glycemic benefit of miglitol.

How serious is the interaction between Darunavir and Miglitol?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose and HbA1c after starting darunavir. Adjust antidiabetic therapy as needed.

What other medicines interact with Miglitol?

MediHelp also lists interactions of Miglitol with, for example, Pramlintide, Aripiprazole, Asenapine. The full list is on the Miglitol page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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