Interactions médicamenteuses
Cholera vaccine + Tigecycline
Gravité: Modérée
Cholera vaccine and Tigecycline: moderate interaction.
Dernière mise à jour
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Résumé
The oral live attenuated cholera vaccine relies on viable bacteria colonizing the gut, and systemic antibiotics with activity against the strain may reduce its effect. Tigecycline is given intravenously, but it has broad activity and may still impair the immune response.
Ce que signifie cette interaction, en termes simples
Cholera vaccine and Tigecycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Pourquoi elle survient
Antibiotic activity against the live attenuated vaccine strain reduces its replication and immunogenicity.
Conduite à tenir
Avoid giving the live oral cholera vaccine during antibiotic therapy and delay vaccination for at least 14 days after the antibiotic course.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Tigecycline
Questions fréquentes
Can I take Cholera vaccine with Tigecycline?
MediHelp rates the interaction as moderate. Cholera vaccine and Tigecycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. The oral live attenuated cholera vaccine relies on viable bacteria colonizing the gut, and systemic antibiotics with activity against the strain may reduce its effect. Tigecycline is given intravenously, but it has broad activity and may still impair the immune response.
How serious is the interaction between Cholera vaccine and Tigecycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving the live oral cholera vaccine during antibiotic therapy and delay vaccination for at least 14 days after the antibiotic course.
What other medicines interact with Tigecycline?
MediHelp also lists interactions of Tigecycline with, for example, Typhoid vaccine live, Bcg vaccine live, Microbiota. The full list is on the Tigecycline page.
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