Interactions médicamenteuses
Deferiprone + Idarubicin
Gravité: Majeure
Deferiprone and Idarubicin: major interaction.
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Résumé
Deferiprone can cause neutropenia and agranulocytosis, and idarubicin is strongly myelosuppressive. Together the risk of severe, potentially fatal infection is increased.
Ce que signifie cette interaction, en termes simples
Deferiprone and Idarubicin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Deferiprone belongs to Miscellaneous; Idarubicin belongs to Oncology.
Pourquoi elle survient
Additive bone marrow suppression (pharmacodynamic).
Conduite à tenir
Avoid if an alternative iron chelation approach is feasible; otherwise monitor absolute neutrophil count more frequently and interrupt deferiprone for neutropenia.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Idarubicin
- Adenovirus types 4 and 7 live + Idarubicin Contre-indiquée
- Belatacept + Idarubicin Majeure
- Cyclophosphamide + Idarubicin Majeure
- Dengue vaccine + Idarubicin Majeure
- Etrasimod + Idarubicin Majeure
- Fingolimod + Idarubicin Majeure
Autres interactions de Deferiprone
- Clozapine + Deferiprone Contre-indiquée
- Abemaciclib + Deferiprone Majeure
- Acalabrutinib + Deferiprone Majeure
- Ado-trastuzumab emtansine + Deferiprone Majeure
- Ado-trastuzumab + Deferiprone Majeure
- Aldesleukin + Deferiprone Majeure
Questions fréquentes
Can I take Deferiprone with Idarubicin?
MediHelp rates the interaction as major. Deferiprone and Idarubicin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Deferiprone can cause neutropenia and agranulocytosis, and idarubicin is strongly myelosuppressive. Together the risk of severe, potentially fatal infection is increased.
How serious is the interaction between Deferiprone and Idarubicin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid if an alternative iron chelation approach is feasible; otherwise monitor absolute neutrophil count more frequently and interrupt deferiprone for neutropenia.
What other medicines interact with Idarubicin?
MediHelp also lists interactions of Idarubicin with, for example, Adenovirus types 4 and 7 live, Belatacept, Cyclophosphamide. The full list is on the Idarubicin page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
