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Interactions médicamenteuses

Delafloxacin + Manganese

Gravité: Modérée

Delafloxacin and Manganese: moderate interaction.

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Résumé

Oral manganese can bind delafloxacin in the gut, reducing its absorption and potentially causing subtherapeutic antibiotic levels and treatment failure.

Ce que signifie cette interaction, en termes simples

Delafloxacin and Manganese can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Delafloxacin belongs to Anti Bacterial; Manganese belongs to Gastrointestinal Tract.

Niveau de preuve: Moderate

Pourquoi elle survient

Divalent metal cations chelate fluoroquinolones in the gastrointestinal tract, reducing absorption.

Conduite à tenir

Give oral delafloxacin at least 2 hours before or 6 hours after manganese-containing products.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Delafloxacin with Manganese?

MediHelp rates the interaction as moderate. Delafloxacin and Manganese can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral manganese can bind delafloxacin in the gut, reducing its absorption and potentially causing subtherapeutic antibiotic levels and treatment failure.

How serious is the interaction between Delafloxacin and Manganese?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral delafloxacin at least 2 hours before or 6 hours after manganese-containing products.

What other medicines interact with Manganese?

MediHelp also lists interactions of Manganese with, for example, Omadacycline, Sarecycline, Baloxavir marboxil. The full list is on the Manganese page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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