Interactions médicamenteuses
Dengue vaccine + Paclitaxel
Gravité: Majeure
Dengue vaccine and Paclitaxel: major interaction.
Dernière mise à jour
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Résumé
Paclitaxel-induced immunosuppression may blunt the response to the dengue vaccine. As the vaccine is live attenuated, vaccination during chemotherapy also carries a risk of vaccine-related infection.
Ce que signifie cette interaction, en termes simples
Dengue vaccine and Paclitaxel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Pourquoi elle survient
Chemotherapy-induced immunosuppression reduces vaccine immune response and permits replication of the live attenuated virus.
Conduite à tenir
Avoid giving the live dengue vaccine during chemotherapy. Delay vaccination until immune recovery, as advised by the oncology team.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Paclitaxel
- Adenovirus types 4 and 7 live + Paclitaxel Majeure
- Cobicistat + Paclitaxel Majeure
- Cyclosporine + Paclitaxel Majeure
- Cyclosporin + Paclitaxel Majeure
- Deferiprone + Paclitaxel Majeure
- Doxorubicin + Paclitaxel Majeure
Questions fréquentes
Can I take Dengue vaccine with Paclitaxel?
MediHelp rates the interaction as major. Dengue vaccine and Paclitaxel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Paclitaxel-induced immunosuppression may blunt the response to the dengue vaccine. As the vaccine is live attenuated, vaccination during chemotherapy also carries a risk of vaccine-related infection.
How serious is the interaction between Dengue vaccine and Paclitaxel?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving the live dengue vaccine during chemotherapy. Delay vaccination until immune recovery, as advised by the oncology team.
What other medicines interact with Paclitaxel?
MediHelp also lists interactions of Paclitaxel with, for example, Adenovirus types 4 and 7 live, Cobicistat, Cyclosporine. The full list is on the Paclitaxel page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
