Interactions médicamenteuses
Dopamine + Selegiline transdermal
Gravité: Contre-indiquée
Dopamine and Selegiline transdermal: contraindicated interaction.
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Résumé
Selegiline is a monoamine oxidase inhibitor, and inhibited MAO greatly potentiates the pressor effect of dopamine. This may cause severe hypertensive crisis.
Ce que signifie cette interaction, en termes simples
Dopamine and Selegiline transdermal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
MAO inhibition reduces dopamine breakdown and increases norepinephrine stores, amplifying sympathomimetic effects.
Conduite à tenir
Avoid; if dopamine is essential, stop selegiline and use a markedly reduced starting dose with close blood pressure monitoring only in an emergency.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Dopamine
- Dihydroergotamine intranasal + Dopamine Contre-indiquée
- Dihydroergotamine + Dopamine Contre-indiquée
- Amitriptyline + Dopamine Majeure
- Clomipramine + Dopamine Majeure
- Desipramine + Dopamine Majeure
- Dextroamphetamine + Dopamine Majeure
Questions fréquentes
Can I take Dopamine with Selegiline transdermal?
MediHelp rates the interaction as contraindicated. Dopamine and Selegiline transdermal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Selegiline is a monoamine oxidase inhibitor, and inhibited MAO greatly potentiates the pressor effect of dopamine. This may cause severe hypertensive crisis.
How serious is the interaction between Dopamine and Selegiline transdermal?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid; if dopamine is essential, stop selegiline and use a markedly reduced starting dose with close blood pressure monitoring only in an emergency.
What other medicines interact with Dopamine?
MediHelp also lists interactions of Dopamine with, for example, Dihydroergotamine intranasal, Dihydroergotamine, Amitriptyline. The full list is on the Dopamine page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.