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Interactions médicamenteuses

Elvitegravir / cobicistat / emtricitabine / tenofovir df + Raltegravir

Gravité: Contre-indiquée

Elvitegravir / cobicistat / emtricitabine / tenofovir df and Raltegravir: contraindicated interaction.

Dernière mise à jour

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Résumé

The elvitegravir-containing product is a complete single-tablet regimen, and adding raltegravir duplicates integrase inhibitor therapy with no established benefit. Safety and efficacy of this combination have not been studied.

Ce que signifie cette interaction, en termes simples

Elvitegravir / cobicistat / emtricitabine / tenofovir df and Raltegravir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Niveau de preuve: Low

Pourquoi elle survient

Therapeutic duplication of two integrase strand transfer inhibitors; no established pharmacokinetic mechanism.

Conduite à tenir

Do not combine; use the complete regimen alone or build a regimen with raltegravir and other appropriate agents.

Questions à poser à votre pharmacien

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Elvitegravir / cobicistat / emtricitabine / tenofovir df with Raltegravir?

MediHelp rates the interaction as contraindicated. Elvitegravir / cobicistat / emtricitabine / tenofovir df and Raltegravir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The elvitegravir-containing product is a complete single-tablet regimen, and adding raltegravir duplicates integrase inhibitor therapy with no established benefit. Safety and efficacy of this combination have not been studied.

How serious is the interaction between Elvitegravir / cobicistat / emtricitabine / tenofovir df and Raltegravir?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; use the complete regimen alone or build a regimen with raltegravir and other appropriate agents.

What other medicines interact with Raltegravir?

MediHelp also lists interactions of Raltegravir with, for example, Aluminum hydroxide / magnesium carbonate, Aluminum hydroxide / magnesium trisilicate, Aluminum hydroxide. The full list is on the Raltegravir page.

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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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