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Interactions médicamenteuses

Cabotegravir + Raltegravir

Gravité: Majeure

Cabotegravir and Raltegravir: major interaction.

Dernière mise à jour

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Résumé

Both are HIV integrase strand transfer inhibitors, so combining them is therapeutically duplicative. Cabotegravir with rilpivirine is intended as a complete regimen and adding raltegravir offers no established benefit.

Ce que signifie cette interaction, en termes simples

Cabotegravir and Raltegravir can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Cabotegravir belongs to Anti Virals; Raltegravir belongs to Anti Virals.

Niveau de preuve: Low

Pourquoi elle survient

Pharmacodynamic duplication of integrase inhibitor therapy, with no established combination benefit.

Conduite à tenir

Do not combine; use one integrase inhibitor within a complete regimen. Choose either raltegravir-based therapy or cabotegravir plus rilpivirine.

Questions à poser à votre pharmacien

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Cabotegravir with Raltegravir?

MediHelp rates the interaction as major. Cabotegravir and Raltegravir can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both are HIV integrase strand transfer inhibitors, so combining them is therapeutically duplicative. Cabotegravir with rilpivirine is intended as a complete regimen and adding raltegravir offers no established benefit.

How serious is the interaction between Cabotegravir and Raltegravir?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; use one integrase inhibitor within a complete regimen. Choose either raltegravir-based therapy or cabotegravir plus rilpivirine.

What other medicines interact with Raltegravir?

MediHelp also lists interactions of Raltegravir with, for example, Elvitegravir / cobicistat / emtricitabine / tenofovir df, Aluminum hydroxide / magnesium carbonate, Aluminum hydroxide / magnesium trisilicate. The full list is on the Raltegravir page.

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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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