Interactions médicamenteuses
Elvitegravir / cobicistat / emtricitabine / tenofovir df + Stavudine
Gravité: Contre-indiquée
Elvitegravir / cobicistat / emtricitabine / tenofovir df and Stavudine: contraindicated interaction.
Dernière mise à jour
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Résumé
This fixed-dose product is a complete HIV regimen and is not intended for use with other antiretrovirals. Adding stavudine duplicates the nucleoside backbone and increases risks of neuropathy, lipoatrophy and lactic acidosis without benefit.
Ce que signifie cette interaction, en termes simples
Elvitegravir / cobicistat / emtricitabine / tenofovir df and Stavudine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Therapeutic duplication of nucleoside reverse transcriptase inhibitors, with additive mitochondrial toxicity.
Conduite à tenir
Do not co-administer; stavudine should be stopped if the single-tablet regimen is used.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Stavudine
- Didanosine + Stavudine Contre-indiquée
- Hydroxycarbamide + Stavudine Contre-indiquée
- Stavudine + Zidovudine Contre-indiquée
- Atidarsagene autotemcel + Stavudine Majeure
- Betibeglogene autotemcel + Stavudine Majeure
- Elivaldogene autotemcel + Stavudine Majeure
Questions fréquentes
Can I take Elvitegravir / cobicistat / emtricitabine / tenofovir df with Stavudine?
MediHelp rates the interaction as contraindicated. Elvitegravir / cobicistat / emtricitabine / tenofovir df and Stavudine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. This fixed-dose product is a complete HIV regimen and is not intended for use with other antiretrovirals. Adding stavudine duplicates the nucleoside backbone and increases risks of neuropathy, lipoatrophy and lactic acidosis without benefit.
How serious is the interaction between Elvitegravir / cobicistat / emtricitabine / tenofovir df and Stavudine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not co-administer; stavudine should be stopped if the single-tablet regimen is used.
What other medicines interact with Stavudine?
MediHelp also lists interactions of Stavudine with, for example, Didanosine, Hydroxycarbamide, Zidovudine. The full list is on the Stavudine page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
