Interactions médicamenteuses
Etrasimod + Pemetrexed
Gravité: Majeure
Etrasimod and Pemetrexed: major interaction.
Dernière mise à jour
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Résumé
Etrasimod lowers circulating lymphocytes, and pemetrexed causes myelosuppression, so the two together may increase susceptibility to infection. The combination has not been formally studied.
Ce que signifie cette interaction, en termes simples
Etrasimod and Pemetrexed can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Etrasimod belongs to Gastrointestinal Tract; Pemetrexed belongs to Oncology.
Pourquoi elle survient
Additive immunosuppression from lymphocyte sequestration by etrasimod and bone marrow suppression by pemetrexed.
Conduite à tenir
Avoid combining where possible, and allow for the lingering effect of etrasimod after it is stopped. If used together, monitor blood counts and watch for infection.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Pemetrexed
- Bacitracin + Pemetrexed Majeure
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Autres interactions de Etrasimod
- Abatacept + Etrasimod Majeure
- Amiodarone + Etrasimod Majeure
- Anagrelide + Etrasimod Majeure
- Anakinra + Etrasimod Majeure
- Anti-thymocyte + Etrasimod Majeure
- Asenapine + Etrasimod Majeure
Questions fréquentes
Can I take Etrasimod with Pemetrexed?
MediHelp rates the interaction as major. Etrasimod and Pemetrexed can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Etrasimod lowers circulating lymphocytes, and pemetrexed causes myelosuppression, so the two together may increase susceptibility to infection. The combination has not been formally studied.
How serious is the interaction between Etrasimod and Pemetrexed?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining where possible, and allow for the lingering effect of etrasimod after it is stopped. If used together, monitor blood counts and watch for infection.
What other medicines interact with Pemetrexed?
MediHelp also lists interactions of Pemetrexed with, for example, Bacitracin, Brexucabtagene autoleucel, Celecoxib. The full list is on the Pemetrexed page.
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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
