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Interactions médicamenteuses

Anti-thymocyte + Etrasimod

Gravité: Majeure

Anti-thymocyte and Etrasimod: major interaction.

Dernière mise à jour

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Résumé

Etrasimod reduces circulating lymphocytes, and anti-thymocyte globulin profoundly depletes T cells. Used together they may cause additive immunosuppression and a higher risk of serious infection. Combined use has not been studied.

Ce que signifie cette interaction, en termes simples

Anti-thymocyte and Etrasimod can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Anti-thymocyte belongs to Miscellaneous; Etrasimod belongs to Gastrointestinal Tract.

Niveau de preuve: Low

Pourquoi elle survient

Additive pharmacodynamic immunosuppression through lymphocyte sequestration (etrasimod) and T-cell depletion (anti-thymocyte globulin).

Conduite à tenir

Avoid combining the two where possible, and allow a sufficient interval after anti-thymocyte globulin before starting etrasimod. If given together, monitor closely for infection and check lymphocyte counts.

Questions à poser à votre pharmacien

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Anti-thymocyte with Etrasimod?

MediHelp rates the interaction as major. Anti-thymocyte and Etrasimod can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Etrasimod reduces circulating lymphocytes, and anti-thymocyte globulin profoundly depletes T cells. Used together they may cause additive immunosuppression and a higher risk of serious infection. Combined use has not been studied.

How serious is the interaction between Anti-thymocyte and Etrasimod?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining the two where possible, and allow a sufficient interval after anti-thymocyte globulin before starting etrasimod. If given together, monitor closely for infection and check lymphocyte counts.

What other medicines interact with Anti-thymocyte?

MediHelp also lists interactions of Anti-thymocyte with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Anti-thymocyte page.

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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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