Interactions médicamenteuses
Golimumab + Measles vaccine
Gravité: Contre-indiquée
Golimumab and Measles vaccine: contraindicated interaction.
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Résumé
Measles vaccine is live attenuated. In patients on golimumab, uncontrolled replication of the vaccine virus could cause disseminated disease, and the immune response may be inadequate.
Ce que signifie cette interaction, en termes simples
Golimumab and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
TNF-alpha blockade impairs immune control of replicating live attenuated virus.
Conduite à tenir
Avoid live vaccines during golimumab therapy; give them at least 4 weeks before starting if possible, and follow labeling or guidelines for the interval after stopping.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Golimumab
- Bcg vaccine live + Golimumab Contre-indiquée
- Etanercept + Golimumab Contre-indiquée
- Golimumab + Influenza virus vaccine quadrivalent intranasal Contre-indiquée
- Golimumab + Measles mumps and rubella vaccine Contre-indiquée
- Golimumab + Measles mumps and rubella vaccine live Contre-indiquée
- Golimumab + Measles mumps rubella and varicella vaccine live Contre-indiquée
Questions fréquentes
Can I take Golimumab with Measles vaccine?
MediHelp rates the interaction as contraindicated. Golimumab and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Measles vaccine is live attenuated. In patients on golimumab, uncontrolled replication of the vaccine virus could cause disseminated disease, and the immune response may be inadequate.
How serious is the interaction between Golimumab and Measles vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during golimumab therapy; give them at least 4 weeks before starting if possible, and follow labeling or guidelines for the interval after stopping.
What other medicines interact with Golimumab?
MediHelp also lists interactions of Golimumab with, for example, Bcg vaccine live, Etanercept, Influenza virus vaccine quadrivalent intranasal. The full list is on the Golimumab page.
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