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Interactions médicamenteuses

Etanercept + Golimumab

Gravité: Contre-indiquée

Etanercept and Golimumab: contraindicated interaction.

Dernière mise à jour

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Résumé

Both agents are TNF-alpha inhibitors, so combining them duplicates therapy without added benefit. Studies of TNF blocker combinations showed more serious infections and adverse events.

Ce que signifie cette interaction, en termes simples

Etanercept and Golimumab are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Etanercept belongs to Musculoskeletal; Golimumab belongs to Musculoskeletal.

Niveau de preuve: Moderate

Pourquoi elle survient

Duplicate TNF-alpha blockade causing additive immunosuppression.

Conduite à tenir

Do not combine two TNF inhibitors. Use a single agent and switch to another class if response is inadequate.

Questions à poser à votre pharmacien

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Etanercept with Golimumab?

MediHelp rates the interaction as contraindicated. Etanercept and Golimumab are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both agents are TNF-alpha inhibitors, so combining them duplicates therapy without added benefit. Studies of TNF blocker combinations showed more serious infections and adverse events.

How serious is the interaction between Etanercept and Golimumab?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine two TNF inhibitors. Use a single agent and switch to another class if response is inadequate.

What other medicines interact with Golimumab?

MediHelp also lists interactions of Golimumab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Golimumab page.

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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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