Drug interactions
Golimumab + Measles vaccine
Severity: Contraindicated
Golimumab and Measles vaccine: contraindicated interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Measles vaccine is live attenuated. In patients on golimumab, uncontrolled replication of the vaccine virus could cause disseminated disease, and the immune response may be inadequate.
What this interaction means in plain words
Golimumab and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Why it happens
TNF-alpha blockade impairs immune control of replicating live attenuated virus.
What to do
Avoid live vaccines during golimumab therapy; give them at least 4 weeks before starting if possible, and follow labeling or guidelines for the interval after stopping.
What to ask your pharmacist
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Other interactions of Golimumab
- Bcg vaccine live + Golimumab Contraindicated
- Etanercept + Golimumab Contraindicated
- Golimumab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Golimumab + Measles mumps and rubella vaccine Contraindicated
- Golimumab + Measles mumps and rubella vaccine live Contraindicated
- Golimumab + Measles mumps rubella and varicella vaccine live Contraindicated
Frequently asked questions
Can I take Golimumab with Measles vaccine?
MediHelp rates the interaction as contraindicated. Golimumab and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Measles vaccine is live attenuated. In patients on golimumab, uncontrolled replication of the vaccine virus could cause disseminated disease, and the immune response may be inadequate.
How serious is the interaction between Golimumab and Measles vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during golimumab therapy; give them at least 4 weeks before starting if possible, and follow labeling or guidelines for the interval after stopping.
What other medicines interact with Golimumab?
MediHelp also lists interactions of Golimumab with, for example, Bcg vaccine live, Etanercept, Influenza virus vaccine quadrivalent intranasal. The full list is on the Golimumab page.
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