Interactions médicamenteuses
Ifosfamide + Measles mumps and rubella vaccine live
Gravité: Contre-indiquée
Ifosfamide and Measles mumps and rubella vaccine live: contraindicated interaction.
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Résumé
MMR vaccine contains live attenuated viruses, which can replicate without control in a patient immunosuppressed by ifosfamide. This can lead to disseminated vaccine-virus disease, and the vaccine response is also reduced.
Ce que signifie cette interaction, en termes simples
Ifosfamide and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Chemotherapy-induced immunosuppression allows unchecked replication of live attenuated virus and impairs the vaccine response.
Conduite à tenir
Avoid live vaccines during ifosfamide therapy and for at least 3 months after it ends, subject to recovery of immune function. Give live vaccines at least 4 weeks before starting chemotherapy when possible.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Ifosfamide
- Adenovirus types 4 and 7 live + Ifosfamide Contre-indiquée
- Ifosfamide + Measles mumps and rubella vaccine Contre-indiquée
- Ifosfamide + Measles mumps rubella and varicella vaccine live Contre-indiquée
- Ifosfamide + Measles vaccine Contre-indiquée
- Ifosfamide + Rotavirus oral vaccine live Contre-indiquée
- Ifosfamide + Rubella vaccine Contre-indiquée
Questions fréquentes
Can I take Ifosfamide with Measles mumps and rubella vaccine live?
MediHelp rates the interaction as contraindicated. Ifosfamide and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. MMR vaccine contains live attenuated viruses, which can replicate without control in a patient immunosuppressed by ifosfamide. This can lead to disseminated vaccine-virus disease, and the vaccine response is also reduced.
How serious is the interaction between Ifosfamide and Measles mumps and rubella vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during ifosfamide therapy and for at least 3 months after it ends, subject to recovery of immune function. Give live vaccines at least 4 weeks before starting chemotherapy when possible.
What other medicines interact with Ifosfamide?
MediHelp also lists interactions of Ifosfamide with, for example, Adenovirus types 4 and 7 live, Measles mumps and rubella vaccine, Measles mumps rubella and varicella vaccine live. The full list is on the Ifosfamide page.
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