Interactions médicamenteuses
Ifosfamide + Measles mumps and rubella vaccine
Gravité: Contre-indiquée
Ifosfamide and Measles mumps and rubella vaccine: contraindicated interaction.
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Résumé
Ifosfamide is a cytotoxic alkylating agent that depletes lymphocytes and neutrophils, so live attenuated measles, mumps, rubella and varicella vaccine viruses may replicate without control. This can lead to disseminated vaccine-strain disease and the vaccine also gives poor protection.
Ce que signifie cette interaction, en termes simples
Ifosfamide and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ifosfamide belongs to Oncology; Measles mumps and rubella vaccine belongs to Miscellaneous.
Pourquoi elle survient
Immunosuppression permits replication of live attenuated vaccine viruses: myelosuppression and lymphocyte depletion
Conduite à tenir
Do not give live vaccines during chemotherapy; vaccinate at least 4 weeks before starting and defer until immune recovery (usually at least 3 months after treatment ends).
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Measles mumps and rubella vaccine
- Adalimumab + Measles mumps and rubella vaccine Contre-indiquée
- Anakinra + Measles mumps and rubella vaccine Contre-indiquée
- Antithymocyte globulin equine + Measles mumps and rubella vaccine Contre-indiquée
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine Contre-indiquée
- Azathioprine + Measles mumps and rubella vaccine Contre-indiquée
- Basiliximab + Measles mumps and rubella vaccine Contre-indiquée
Autres interactions de Ifosfamide
- Adenovirus types 4 and 7 live + Ifosfamide Contre-indiquée
- Ifosfamide + Measles mumps and rubella vaccine live Contre-indiquée
- Ifosfamide + Measles mumps rubella and varicella vaccine live Contre-indiquée
- Ifosfamide + Measles vaccine Contre-indiquée
- Ifosfamide + Rotavirus oral vaccine live Contre-indiquée
- Ifosfamide + Rubella vaccine Contre-indiquée
Questions fréquentes
Can I take Ifosfamide with Measles mumps and rubella vaccine?
MediHelp rates the interaction as contraindicated. Ifosfamide and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ifosfamide is a cytotoxic alkylating agent that depletes lymphocytes and neutrophils, so live attenuated measles, mumps, rubella and varicella vaccine viruses may replicate without control. This can lead to disseminated vaccine-strain disease and the vaccine also gives poor protection.
How serious is the interaction between Ifosfamide and Measles mumps and rubella vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live vaccines during chemotherapy; vaccinate at least 4 weeks before starting and defer until immune recovery (usually at least 3 months after treatment ends).
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
