Interactions médicamenteuses
Ifosfamide + Rotavirus oral vaccine live
Gravité: Contre-indiquée
Ifosfamide and Rotavirus oral vaccine live: contraindicated interaction.
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Résumé
Rotavirus vaccine contains live attenuated virus, which could replicate excessively in a patient immunosuppressed by ifosfamide. This raises the risk of prolonged vaccine-virus gastrointestinal infection, and the vaccine response may be reduced.
Ce que signifie cette interaction, en termes simples
Ifosfamide and Rotavirus oral vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Chemotherapy-induced immunosuppression allows unchecked replication of live attenuated virus and impairs the vaccine response.
Conduite à tenir
Avoid live vaccines during ifosfamide therapy and for at least 3 months after it ends. Seek specialist advice if an infant is exposed through a treated household member.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Ifosfamide
- Adenovirus types 4 and 7 live + Ifosfamide Contre-indiquée
- Ifosfamide + Measles mumps and rubella vaccine Contre-indiquée
- Ifosfamide + Measles mumps and rubella vaccine live Contre-indiquée
- Ifosfamide + Measles mumps rubella and varicella vaccine live Contre-indiquée
- Ifosfamide + Measles vaccine Contre-indiquée
- Ifosfamide + Rubella vaccine Contre-indiquée
Questions fréquentes
Can I take Ifosfamide with Rotavirus oral vaccine live?
MediHelp rates the interaction as contraindicated. Ifosfamide and Rotavirus oral vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Rotavirus vaccine contains live attenuated virus, which could replicate excessively in a patient immunosuppressed by ifosfamide. This raises the risk of prolonged vaccine-virus gastrointestinal infection, and the vaccine response may be reduced.
How serious is the interaction between Ifosfamide and Rotavirus oral vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during ifosfamide therapy and for at least 3 months after it ends. Seek specialist advice if an infant is exposed through a treated household member.
What other medicines interact with Ifosfamide?
MediHelp also lists interactions of Ifosfamide with, for example, Adenovirus types 4 and 7 live, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Ifosfamide page.
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