Interactions médicamenteuses
Influenza virus vaccine quadrivalent intranasal + Sirolimus
Gravité: Contre-indiquée
Influenza virus vaccine quadrivalent intranasal and Sirolimus: contraindicated interaction.
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Résumé
The intranasal influenza vaccine contains live attenuated virus, which could replicate in immunosuppressed patients on sirolimus and cause illness. The vaccine response may also be inadequate.
Ce que signifie cette interaction, en termes simples
Influenza virus vaccine quadrivalent intranasal and Sirolimus are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Sirolimus immunosuppression permits replication of live attenuated virus and blunts vaccine response.
Conduite à tenir
Do not use the live intranasal vaccine; give an inactivated injectable influenza vaccine instead.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Sirolimus
- Adenovirus types 4 and 7 live + Sirolimus Contre-indiquée
- Bcg vaccine live + Sirolimus Contre-indiquée
- Ketoconazole + Sirolimus Contre-indiquée
- Levoketoconazole + Sirolimus Contre-indiquée
- Measles mumps and rubella vaccine live + Sirolimus Contre-indiquée
- Measles mumps and rubella vaccine + Sirolimus Contre-indiquée
Questions fréquentes
Can I take Influenza virus vaccine quadrivalent intranasal with Sirolimus?
MediHelp rates the interaction as contraindicated. Influenza virus vaccine quadrivalent intranasal and Sirolimus are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The intranasal influenza vaccine contains live attenuated virus, which could replicate in immunosuppressed patients on sirolimus and cause illness. The vaccine response may also be inadequate.
How serious is the interaction between Influenza virus vaccine quadrivalent intranasal and Sirolimus?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use the live intranasal vaccine; give an inactivated injectable influenza vaccine instead.
What other medicines interact with Sirolimus?
MediHelp also lists interactions of Sirolimus with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Ketoconazole. The full list is on the Sirolimus page.
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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
