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Interactions médicamenteuses

Iodine + Propylthiouracil

Gravité: Modérée

Iodine and Propylthiouracil: moderate interaction.

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Résumé

Systemic iodine affects thyroid hormone production and release, so combining it with an antithyroid drug may lead to unpredictable thyroid control. Excess iodine can add to hypothyroid or goitrogenic effects.

Ce que signifie cette interaction, en termes simples

Iodine and Propylthiouracil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Iodine belongs to Dermatology; Propylthiouracil belongs to Endocrine.

Niveau de preuve: Moderate

Pourquoi elle survient

Excess iodide inhibits thyroid hormone release and synthesis, adding to thyroid peroxidase inhibition.

Conduite à tenir

Monitor thyroid function and avoid unnecessary iodine supplements during propylthiouracil therapy unless used deliberately, for example before thyroid surgery.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Iodine with Propylthiouracil?

MediHelp rates the interaction as moderate. Iodine and Propylthiouracil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Systemic iodine affects thyroid hormone production and release, so combining it with an antithyroid drug may lead to unpredictable thyroid control. Excess iodine can add to hypothyroid or goitrogenic effects.

How serious is the interaction between Iodine and Propylthiouracil?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor thyroid function and avoid unnecessary iodine supplements during propylthiouracil therapy unless used deliberately, for example before thyroid surgery.

What other medicines interact with Propylthiouracil?

MediHelp also lists interactions of Propylthiouracil with, for example, Carbamazepine, Clozapine, Methimazole. The full list is on the Propylthiouracil page.

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