Interactions médicamenteuses
Lomustine + Measles vaccine
Gravité: Contre-indiquée
Lomustine and Measles vaccine: contraindicated interaction.
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Résumé
Live measles vaccine can cause progressive or disseminated measles infection in patients immunosuppressed by lomustine. Vaccine response may also be inadequate.
Ce que signifie cette interaction, en termes simples
Lomustine and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Cytotoxic immunosuppression impairs control of live vaccine virus replication and reduces the immune response.
Conduite à tenir
Avoid during lomustine therapy and defer until immune recovery, generally at least 3 months after chemotherapy ends. Consider immunoglobulin prophylaxis if exposed to measles.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Lomustine
- Adenovirus types 4 and 7 live + Lomustine Contre-indiquée
- Bcg vaccine live + Lomustine Contre-indiquée
- Influenza virus vaccine quadrivalent intranasal + Lomustine Contre-indiquée
- Lomustine + Measles mumps and rubella vaccine Contre-indiquée
- Lomustine + Measles mumps and rubella vaccine live Contre-indiquée
- Lomustine + Measles mumps rubella and varicella vaccine live Contre-indiquée
Questions fréquentes
Can I take Lomustine with Measles vaccine?
MediHelp rates the interaction as contraindicated. Lomustine and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Live measles vaccine can cause progressive or disseminated measles infection in patients immunosuppressed by lomustine. Vaccine response may also be inadequate.
How serious is the interaction between Lomustine and Measles vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid during lomustine therapy and defer until immune recovery, generally at least 3 months after chemotherapy ends. Consider immunoglobulin prophylaxis if exposed to measles.
What other medicines interact with Lomustine?
MediHelp also lists interactions of Lomustine with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Lomustine page.
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