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Interactions médicamenteuses

Lomustine + Measles mumps and rubella vaccine

Gravité: Contre-indiquée

Lomustine and Measles mumps and rubella vaccine: contraindicated interaction.

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Résumé

Lomustine is a myelosuppressive cytotoxic agent, and live vaccine replication may be uncontrolled, risking disseminated vaccine-strain infection. The vaccine response may also be inadequate.

Ce que signifie cette interaction, en termes simples

Lomustine and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Lomustine belongs to Oncology; Measles mumps and rubella vaccine belongs to Miscellaneous.

Niveau de preuve: Moderate

Pourquoi elle survient

Chemotherapy-induced immunosuppression permits unchecked replication of live attenuated virus.

Conduite à tenir

Do not give live vaccines during chemotherapy; defer until immune recovery, typically at least 3 months after stopping.

Questions à poser à votre pharmacien

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Lomustine with Measles mumps and rubella vaccine?

MediHelp rates the interaction as contraindicated. Lomustine and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Lomustine is a myelosuppressive cytotoxic agent, and live vaccine replication may be uncontrolled, risking disseminated vaccine-strain infection. The vaccine response may also be inadequate.

How serious is the interaction between Lomustine and Measles mumps and rubella vaccine?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live vaccines during chemotherapy; defer until immune recovery, typically at least 3 months after stopping.

What other medicines interact with Measles mumps and rubella vaccine?

MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.

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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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