दवा संदर्भ
Etuvetidigene autotemcel
Etuvetidigene autotemcel is a medicine in the class miscellaneous.
- दवा वर्ग: Miscellaneous
अंतिम अपडेट स्रोत: US FDA label
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
मुख्य तथ्य
- दवा वर्ग
- Miscellaneous
- सामान्य रूप
- इंजेक्शन
- ब्रांड नाम
- 1
- देश और बाज़ार
- 1
यह कैसे काम करती है
Adds full-length copies of the human WAS cDNA into the patient's hematopoietic stem cells by lentiviral vector transduction. After infusion the modified cells engraft in bone marrow and repopulate the hematopoietic compartment, and their progeny express WAS protein (WASP).
वयस्कों की सामान्य खुराक (लेबल सारांश)
Wiskott-Aldrich Syndrome: minimum recommended dose 7 × 10 6 CD34 + cells/kg based on body weight at infusion, single-dose intravenous infusion via central venous catheter; maximum volume must remain < 20% of estimated plasma volume
गर्भावस्था और स्तनपान
- गर्भावस्था
- Unsafe One-time gene therapy (own modified stem cells). No data in pregnancy. It must not be given during pregnancy because of the risks of the conditioning chemotherapy. Confirm a negative pregnancy test first; use contraception from stem-cell collection until at least 6 months after the infusion.
- स्तनपान
- Unsafe No data on presence in milk. Nearly all patients are boys (X-linked disease). Because of the risks of conditioning chemotherapy, breastfeeding must stop during conditioning; afterwards follow the advice for the conditioning drugs.
रिपोर्ट किए गए दुष्प्रभाव
- Catheter related infection
- Bacterial and viral infections
- Diarrhea
- Vomiting
- Stomatitis
- Liver injury
प्रतिसंकेत
- Hypersensitivity to the active substance or to any of the excipients
- Previous HSCT within 6 months prior to treatment, or HSCT with evidence of residual donor cells
- Previous treatment with hematopoietic stem cell gene therapy
किन्हें सावधानी रखनी चाहिए
- Hypersensitivity and infusion-related reactions, including anaphylaxis, may occur due to DMSO; monitor during and after infusion
- Engraftment failure may occur; if so, infuse non-transduced back-up stem cells
- Severe cytopenias occur for several weeks; monitor for at least 8 weeks
गर्भावस्था या स्तनपान, किडनी या लिवर के रोग, एलर्जी और आप जो भी अन्य दवा या सप्लीमेंट लेते हैं, उसके बारे में अपने फार्मासिस्ट या डॉक्टर को बताएँ।
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Etuvetidigene autotemcel का पूरा मोनोग्राफ खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें: खुराक, गर्भावस्था और स्तनपान, दुष्प्रभाव, चेतावनियाँ और सभी इंटरैक्शन।
- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- How to give it
- Patient counselling points
- IV preparation and dilution
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
इसी वर्ग की अन्य दवाएँ
अक्सर पूछे जाने वाले प्रश्न
What is Etuvetidigene autotemcel used for?
Etuvetidigene autotemcel is a medicine in the class miscellaneous.
What side effects have been reported with Etuvetidigene autotemcel?
Catheter related infection, Bacterial and viral infections, Diarrhea, Vomiting, Stomatitis, Liver injury.
Can Etuvetidigene autotemcel be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. One-time gene therapy (own modified stem cells). No data in pregnancy. It must not be given during pregnancy because of the risks of the conditioning chemotherapy. Confirm a negative pregnancy test first; use contraception from stem-cell collection until at least 6 months after the infusion. Breastfeeding: Unsafe. No data on presence in milk. Nearly all patients are boys (X-linked disease). Because of the risks of conditioning chemotherapy, breastfeeding must stop during conditioning; afterwards follow the advice for the conditioning drugs.
What does Etuvetidigene autotemcel interact with?
MediHelp does not list a checked interaction for Etuvetidigene autotemcel yet. Always tell your pharmacist about every medicine you take.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
