दवा संदर्भ
Ticagrelor
Ticagrelor is a medicine in the class cardiovascular. It is used for acute coronary syndrome.
- दवा वर्ग: Cardiovascular
- उपयोग: acute coronary syndrome
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
मुख्य तथ्य
- दवा वर्ग
- Cardiovascular
- ATC कोड
- B01AC24
- सामान्य रूप
- टैबलेट
- सामान्य मात्राएँ
- 90 mg, 60 mg
- ज्ञात अंतःक्रियाएँ
- 166 (निषिद्ध: 3 · गंभीर: 80 · मध्यम: 57 · हल्की: 26)
- ब्रांड नाम
- 15
- देश और बाज़ार
- 6
उपयोग
यह कैसे काम करती है
Ticagrelor and its major metabolite reversibly interact with the platelet P2Y12 ADP-receptor to prevent signal transduction and platelet activation, Ticagrelor and its active metabolite are approximately equipotent, Patients can be transitioned from clopidogrel to ticagrelor without interruption of antiplatelet effect
वयस्कों की सामान्य खुराक (लेबल सारांश)
Acute Coronary Syndrome or History of MI (Loading dose) (following ACS event): 180 mg PO x 1 dose
गर्भावस्था और स्तनपान
- गर्भावस्था
- Unknown Case reports have not shown a drug-related risk; in rats and rabbits it caused structural abnormalities at 5-7 times the human dose. UK label: not recommended in pregnancy; use contraception. If needed after a coronary stent, clopidogrel has more data; plan delivery around bleeding risk.
- स्तनपान
- Unknown No human milk data; it reaches rat milk at higher levels than plasma. US label: not recommended; UK: decide whether to stop breastfeeding or the drug. LactMed: over 99% protein bound, so milk levels are likely low; prefer an alternative, especially for a newborn; watch for bruising.
रिपोर्ट किए गए दुष्प्रभाव
- Diarrhea
- Nausea
- Dizziness
- Dyspnea
- Bleeding
- Ventricular pauses
बॉक्स्ड चेतावनियाँ
- Bleeding risk Like other antiplatelet agents, can cause significant, sometimes fatal, bleeding Do not use with active pathological bleeding or a history of intracranial hemorrhage Do not start in patients planned to undergo urgent coronary artery bypass graft surgery (CABG); when possible, discontinue at least 5 days prior to any surgery Suspect bleeding in any patient who is hypotensive and has recently undergone coronary angiography, percutaneous coronary intervention (PCI), CABG, or other surgical procedures after starting ticagrelor If possible, manage bleeding without disc…
प्रतिसंकेत
- History of intracranial hemorrhage (ICH)
- Active pathologic bleeding (eg, peptic ulcer, ICH)
किन्हें सावधानी रखनी चाहिए
- Avoid use with severe hepatic impairment, which may increase ticagrelor serum levels
- Reported to cause false-negative results in platelet functional tests (eg, HIPA assay for HIT)
- Can cause ventricular pauses; bradyarrhythmias, including AV block reported
गर्भावस्था या स्तनपान, किडनी या लिवर के रोग, एलर्जी और आप जो भी अन्य दवा या सप्लीमेंट लेते हैं, उसके बारे में अपने फार्मासिस्ट या डॉक्टर को बताएँ।
मुख्य इंटरैक्शन (166)
- Itraconazole + Ticagrelor Contraindicated
- Ketoconazole + Ticagrelor Contraindicated
- Levoketoconazole + Ticagrelor Contraindicated
- Abciximab + Ticagrelor Major
- Abrocitinib + Ticagrelor Major
- Acalabrutinib + Ticagrelor Major
- Acetylsalicylic acid + Ticagrelor Major
- Alteplase + Ticagrelor Major
- Apalutamide + Ticagrelor Major
- Aspirin + Ticagrelor Major
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Ticagrelor का पूरा मोनोग्राफ खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें: खुराक, गर्भावस्था और स्तनपान, दुष्प्रभाव, चेतावनियाँ और सभी इंटरैक्शन।
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
इसी वर्ग की अन्य दवाएँ
अक्सर पूछे जाने वाले प्रश्न
What is Ticagrelor used for?
Ticagrelor is a medicine in the class cardiovascular. It is used for Acute coronary syndrome, Coronary artery disease, Myocardial infarction, Stroke, Transient ischemic attack.
What side effects have been reported with Ticagrelor?
Diarrhea, Nausea, Dizziness, Dyspnea, Bleeding, Ventricular pauses. Serious warning: Bleeding risk Like other antiplatelet agents, can cause significant, sometimes fatal, bleeding Do not use with active pathological bleeding or a history of intracranial hemorrhage Do not start in patients planned to undergo urgent coronary artery bypass graft surgery (CABG); when possible,…
Can Ticagrelor be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Case reports have not shown a drug-related risk; in rats and rabbits it caused structural abnormalities at 5-7 times the human dose. UK label: not recommended in pregnancy; use contraception. If needed after a coronary stent, clopidogrel has more data; plan delivery around bleeding risk. Breastfeeding: Unknown. No human milk data; it reaches rat milk at higher levels than plasma. US label: not recommended; UK: decide whether to stop breastfeeding or the drug. LactMed: over 99% protein bound, so milk levels are likely low; prefer an alternative, especially for a newborn; watch for bruising.
What does Ticagrelor interact with?
MediHelp lists 166 known interactions for Ticagrelor. Contraindicated: 3 · Major: 80 · Moderate: 57 · Minor: 26. The most serious include Itraconazole, Ketoconazole, Levoketoconazole.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
