दवाओं की अंतःक्रिया
Chloramphenicol + Conivaptan
गंभीरता: गंभीर
Chloramphenicol and Conivaptan: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Chloramphenicol can inhibit CYP3A4 and may increase conivaptan concentrations, raising the risk of overly rapid sodium correction and osmotic demyelination. Conivaptan is contraindicated with strong CYP3A inhibitors, but chloramphenicol's inhibition is less well characterized.
इस इंटरैक्शन का सरल भाषा में अर्थ
Chloramphenicol and Conivaptan can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
ऐसा क्यों होता है
Inhibition of CYP3A4 by chloramphenicol decreases conivaptan metabolism.
क्या करें
Avoid the combination where possible; if used, monitor serum sodium frequently and watch for overcorrection.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Chloramphenicol और Conivaptan की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Chloramphenicol के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Chloramphenicol with Conivaptan?
MediHelp rates the interaction as major. Chloramphenicol and Conivaptan can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Chloramphenicol can inhibit CYP3A4 and may increase conivaptan concentrations, raising the risk of overly rapid sodium correction and osmotic demyelination. Conivaptan is contraindicated with strong CYP3A inhibitors, but chloramphenicol's inhibition is less well characterized.
How serious is the interaction between Chloramphenicol and Conivaptan?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible; if used, monitor serum sodium frequently and watch for overcorrection.
What other medicines interact with Chloramphenicol?
MediHelp also lists interactions of Chloramphenicol with, for example, Adagrasib, Avapritinib, Bcg vaccine live. The full list is on the Chloramphenicol page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
