दवाओं की अंतःक्रिया
Cimetidine + Pefloxacin
गंभीरता: मध्यम
Cimetidine and Pefloxacin: moderate interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Cimetidine has been reported to slow pefloxacin elimination, raising its levels and half-life. Increased fluoroquinolone adverse effects such as CNS effects are possible but this is rarely significant.
इस इंटरैक्शन का सरल भाषा में अर्थ
Cimetidine and Pefloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cimetidine belongs to Gastrointestinal Tract; Pefloxacin belongs to Anti Bacterial.
ऐसा क्यों होता है
Cimetidine inhibits hepatic oxidative metabolism of pefloxacin, reducing its clearance.
क्या करें
Monitor for CNS effects and tendon or gastrointestinal adverse effects, and consider lowering the pefloxacin dose in hepatic impairment or the elderly.
फार्मासिस्ट से क्या पूछें
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Cimetidine और Pefloxacin की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Cimetidine के अन्य इंटरैक्शन
- Cimetidine + Dofetilide निषिद्ध
- Cimetidine + Fezolinetant निषिद्ध
- Alfentanil + Cimetidine गंभीर
- Atazanavir + Cimetidine गंभीर
- Carmustine + Cimetidine गंभीर
- Cimetidine + Citalopram गंभीर
Pefloxacin के अन्य इंटरैक्शन
- Pefloxacin + Tizanidine निषिद्ध
- Clozapine + Pefloxacin गंभीर
- Duloxetine + Pefloxacin गंभीर
- Pefloxacin + Theophylline गंभीर
- Asenapine + Pefloxacin मध्यम
- Caffeine + Pefloxacin मध्यम
अक्सर पूछे जाने वाले प्रश्न
Can I take Cimetidine with Pefloxacin?
MediHelp rates the interaction as moderate. Cimetidine and Pefloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cimetidine has been reported to slow pefloxacin elimination, raising its levels and half-life. Increased fluoroquinolone adverse effects such as CNS effects are possible but this is rarely significant.
How serious is the interaction between Cimetidine and Pefloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for CNS effects and tendon or gastrointestinal adverse effects, and consider lowering the pefloxacin dose in hepatic impairment or the elderly.
What other medicines interact with Cimetidine?
MediHelp also lists interactions of Cimetidine with, for example, Dofetilide, Fezolinetant, Alfentanil. The full list is on the Cimetidine page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
