दवाओं की अंतःक्रिया
Ciprofloxacin + Theophylline
गंभीरता: गंभीर
Ciprofloxacin and Theophylline: major interaction.
अंतिम अपडेट स्रोत: US FDA label
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Ciprofloxacin reduces theophylline clearance and can raise serum theophylline concentrations substantially in some patients. This can lead to nausea, tachycardia, arrhythmias and seizures. Elderly patients, those with high baseline levels, liver disease or heart failure, and smokers who stop are at greater risk.
इस इंटरैक्शन का सरल भाषा में अर्थ
Ciprofloxacin and Theophylline can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Ciprofloxacin belongs to Anti Bacterial; Theophylline belongs to Respiratory.
ऐसा क्यों होता है
Ciprofloxacin inhibits CYP1A2, the main enzyme metabolising theophylline, decreasing its clearance.
क्या करें
Prefer an antibiotic that does not inhibit CYP1A2. If ciprofloxacin is needed, measure theophylline levels before and during therapy and reduce the theophylline dose empirically.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Ciprofloxacin और Theophylline की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
संदर्भ
Theophylline के अन्य इंटरैक्शन
- Riociguat + Theophylline निषिद्ध
- Adenosine + Theophylline गंभीर
- Apalutamide + Theophylline गंभीर
- Bupropion + Theophylline गंभीर
- Carvedilol + Theophylline गंभीर
- Cimetidine + Theophylline गंभीर
Ciprofloxacin के अन्य इंटरैक्शन
- Agomelatine + Ciprofloxacin निषिद्ध
- Ciprofloxacin + Fezolinetant निषिद्ध
- Ciprofloxacin + Thioridazine निषिद्ध
- Ciprofloxacin + Tizanidine निषिद्ध
- Ciprofloxacin + Vandetanib निषिद्ध
- Alosetron + Ciprofloxacin गंभीर
अक्सर पूछे जाने वाले प्रश्न
Can I take Ciprofloxacin with Theophylline?
MediHelp rates the interaction as major. Ciprofloxacin and Theophylline can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Ciprofloxacin reduces theophylline clearance and can raise serum theophylline concentrations substantially in some patients. This can lead to nausea, tachycardia, arrhythmias and seizures. Elderly patients, those with high baseline levels, liver disease or heart failure, and smokers who stop are at greater risk.
How serious is the interaction between Ciprofloxacin and Theophylline?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Prefer an antibiotic that does not inhibit CYP1A2. If ciprofloxacin is needed, measure theophylline levels before and during therapy and reduce the theophylline dose empirically.
What other medicines interact with Theophylline?
MediHelp also lists interactions of Theophylline with, for example, Riociguat, Adenosine, Apalutamide. The full list is on the Theophylline page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
