सामग्री पर जाएँ

दवाओं की अंतःक्रिया

Clarithromycin + Voclosporin

गंभीरता: निषिद्ध

Clarithromycin and Voclosporin: contraindicated interaction.

अंतिम अपडेट

केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।

इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।

सारांश

Clarithromycin markedly increases voclosporin concentrations. This raises the risk of nephrotoxicity, hypertension, neurotoxicity, QT prolongation and over-immunosuppression. Voclosporin labeling contraindicates strong CYP3A4 inhibitors.

इस इंटरैक्शन का सरल भाषा में अर्थ

Clarithromycin and Voclosporin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Clarithromycin belongs to Anti Bacterial; Voclosporin belongs to Miscellaneous.

साक्ष्य स्तर: High

ऐसा क्यों होता है

Strong CYP3A4 inhibition (and P-glycoprotein inhibition) decreases voclosporin clearance.

क्या करें

Avoid the combination and use a non-inhibiting antibiotic such as azithromycin if suitable. If a macrolide course cannot be avoided, hold voclosporin per specialist guidance and monitor renal function and blood pressure.

फार्मासिस्ट से क्या पूछें

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ सदस्यों के लिए

पूरा पेज खोलें

Clarithromycin और Voclosporin की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।

अक्सर पूछे जाने वाले प्रश्न

Can I take Clarithromycin with Voclosporin?

MediHelp rates the interaction as contraindicated. Clarithromycin and Voclosporin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Clarithromycin markedly increases voclosporin concentrations. This raises the risk of nephrotoxicity, hypertension, neurotoxicity, QT prolongation and over-immunosuppression. Voclosporin labeling contraindicates strong CYP3A4 inhibitors.

How serious is the interaction between Clarithromycin and Voclosporin?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and use a non-inhibiting antibiotic such as azithromycin if suitable. If a macrolide course cannot be avoided, hold voclosporin per specialist guidance and monitor renal function and blood pressure.

What other medicines interact with Clarithromycin?

MediHelp also lists interactions of Clarithromycin with, for example, Astemizole, Avanafil, Cisapride. The full list is on the Clarithromycin page.

MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर

MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।

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