दवाओं की अंतःक्रिया
Dexamethasone + Glycerol phenylbutyrate
गंभीरता: गंभीर
Dexamethasone and Glycerol phenylbutyrate: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Corticosteroids promote protein catabolism and can raise ammonia, working against the ammonia-lowering aim of glycerol phenylbutyrate in urea cycle disorders. This can precipitate hyperammonemia.
इस इंटरैक्शन का सरल भाषा में अर्थ
Dexamethasone and Glycerol phenylbutyrate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Dexamethasone belongs to Endocrine; Glycerol phenylbutyrate belongs to Miscellaneous.
ऐसा क्यों होता है
Glucocorticoid-induced protein breakdown increases nitrogen load and plasma ammonia, opposing the nitrogen scavenging action.
क्या करें
Monitor plasma ammonia closely and adjust the glycerol phenylbutyrate dose or protein intake if ammonia rises; avoid unnecessary steroid use.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Dexamethasone और Glycerol phenylbutyrate की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Dexamethasone के अन्य इंटरैक्शन
Glycerol phenylbutyrate के अन्य इंटरैक्शन
- Glycerol phenylbutyrate + Sodium valproate गंभीर
- Glycerol phenylbutyrate + Valproic acid गंभीर
- Cyclosporin + Glycerol phenylbutyrate मध्यम
- Dexamethasone-neomycin-polymyxin + Glycerol phenylbutyrate मध्यम
- Dexamethasone-tobramycin + Glycerol phenylbutyrate मध्यम
- Fludrocortisone + Glycerol phenylbutyrate मध्यम
अक्सर पूछे जाने वाले प्रश्न
Can I take Dexamethasone with Glycerol phenylbutyrate?
MediHelp rates the interaction as major. Dexamethasone and Glycerol phenylbutyrate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Corticosteroids promote protein catabolism and can raise ammonia, working against the ammonia-lowering aim of glycerol phenylbutyrate in urea cycle disorders. This can precipitate hyperammonemia.
How serious is the interaction between Dexamethasone and Glycerol phenylbutyrate?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor plasma ammonia closely and adjust the glycerol phenylbutyrate dose or protein intake if ammonia rises; avoid unnecessary steroid use.
What other medicines interact with Dexamethasone?
MediHelp also lists interactions of Dexamethasone with, for example, Bcg vaccine live, Mifepristone, Rilpivirine. The full list is on the Dexamethasone page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
