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Dexamethasone-tobramycin + Glycerol phenylbutyrate

गंभीरता: मध्यम

Dexamethasone-tobramycin and Glycerol phenylbutyrate: moderate interaction.

अंतिम अपडेट

केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।

इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।

सारांश

Corticosteroids promote protein catabolism and can raise plasma ammonia, opposing the ammonia-lowering effect of glycerol phenylbutyrate in urea cycle disorders. The concern is mainly with systemic dexamethasone.

इस इंटरैक्शन का सरल भाषा में अर्थ

Dexamethasone-tobramycin and Glycerol phenylbutyrate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Dexamethasone-tobramycin belongs to Anti Bacterial; Glycerol phenylbutyrate belongs to Miscellaneous.

साक्ष्य स्तर: Moderate

ऐसा क्यों होता है

Corticosteroid-induced protein breakdown increases nitrogen load and ammonia.

क्या करें

Monitor plasma ammonia closely if systemic corticosteroids are used and adjust the phenylbutyrate dose as needed.

फार्मासिस्ट से क्या पूछें

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ सदस्यों के लिए

पूरा पेज खोलें

Dexamethasone-tobramycin और Glycerol phenylbutyrate की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।

अक्सर पूछे जाने वाले प्रश्न

Can I take Dexamethasone-tobramycin with Glycerol phenylbutyrate?

MediHelp rates the interaction as moderate. Dexamethasone-tobramycin and Glycerol phenylbutyrate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Corticosteroids promote protein catabolism and can raise plasma ammonia, opposing the ammonia-lowering effect of glycerol phenylbutyrate in urea cycle disorders. The concern is mainly with systemic dexamethasone.

How serious is the interaction between Dexamethasone-tobramycin and Glycerol phenylbutyrate?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor plasma ammonia closely if systemic corticosteroids are used and adjust the phenylbutyrate dose as needed.

What other medicines interact with Dexamethasone-tobramycin?

MediHelp also lists interactions of Dexamethasone-tobramycin with, for example, Capreomycin, Carboplatin, Ciprofloxacin. The full list is on the Dexamethasone-tobramycin page.

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