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Elagolix + Ethinyl estradiol-levonorgestrel

गंभीरता: गंभीर

Elagolix and Ethinyl estradiol-levonorgestrel: major interaction.

अंतिम अपडेट

केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।

इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।

सारांश

Elagolix suppresses the hypothalamic-pituitary-ovarian axis, and estrogen-containing contraceptives are expected to oppose its effect and reduce its efficacy. Elagolix is also not a reliable contraceptive when combined with hormonal methods, and its own effect on contraceptive efficacy is uncertain.

इस इंटरैक्शन का सरल भाषा में अर्थ

Elagolix and Ethinyl estradiol-levonorgestrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Elagolix belongs to Musculoskeletal; Ethinyl estradiol-levonorgestrel belongs to Endocrine.

साक्ष्य स्तर: Moderate

ऐसा क्यों होता है

Pharmacodynamic antagonism between exogenous estrogen/progestin and GnRH receptor antagonism by elagolix.

क्या करें

Avoid combining the two drugs and use non-hormonal contraception during elagolix and for about one week after stopping. Reassess symptom control if hormonal contraception is considered necessary.

फार्मासिस्ट से क्या पूछें

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ सदस्यों के लिए

पूरा पेज खोलें

Elagolix और Ethinyl estradiol-levonorgestrel की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

वेब पर Pro+ को 14 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।

अक्सर पूछे जाने वाले प्रश्न

Can I take Elagolix with Ethinyl estradiol-levonorgestrel?

MediHelp rates the interaction as major. Elagolix and Ethinyl estradiol-levonorgestrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Elagolix suppresses the hypothalamic-pituitary-ovarian axis, and estrogen-containing contraceptives are expected to oppose its effect and reduce its efficacy. Elagolix is also not a reliable contraceptive when combined with hormonal methods, and its own effect on contraceptive efficacy is uncertain.

How serious is the interaction between Elagolix and Ethinyl estradiol-levonorgestrel?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining the two drugs and use non-hormonal contraception during elagolix and for about one week after stopping. Reassess symptom control if hormonal contraception is considered necessary.

What other medicines interact with Ethinyl estradiol-levonorgestrel?

MediHelp also lists interactions of Ethinyl estradiol-levonorgestrel with, for example, Fezolinetant, Ombitasvir / paritaprevir / ritonavir and dasabuvir, Tranexamic acid. The full list is on the Ethinyl estradiol-levonorgestrel page.

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