दवाओं की अंतःक्रिया
Rifampicin + Thalidomide
गंभीरता: गंभीर
Rifampicin and Thalidomide: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Rifampicin is a strong enzyme inducer that substantially lowers hormonal contraceptive levels, risking contraceptive failure. With thalidomide, a pregnancy would carry a risk of severe birth defects.
इस इंटरैक्शन का सरल भाषा में अर्थ
Rifampicin and Thalidomide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Rifampicin belongs to Anti Bacterial; Thalidomide belongs to Miscellaneous.
ऐसा क्यों होता है
Induction of CYP3A4 and other enzymes by rifampicin increases contraceptive hormone metabolism.
क्या करें
Do not depend on hormonal contraceptives; use a non-hormonal highly effective method such as a copper IUD plus a barrier method during and for several weeks after rifampicin.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Rifampicin और Thalidomide की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 7 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Thalidomide के अन्य इंटरैक्शन
Rifampicin के अन्य इंटरैक्शन
- Cabotegravir + Rifampicin निषिद्ध
- Delamanid + Rifampicin निषिद्ध
- Doravirine + Rifampicin निषिद्ध
- Ensitrelvir + Rifampicin निषिद्ध
- Fostemsavir + Rifampicin निषिद्ध
- Isavuconazole + Rifampicin निषिद्ध
अक्सर पूछे जाने वाले प्रश्न
Can I take Rifampicin with Thalidomide?
MediHelp rates the interaction as major. Rifampicin and Thalidomide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Rifampicin is a strong enzyme inducer that substantially lowers hormonal contraceptive levels, risking contraceptive failure. With thalidomide, a pregnancy would carry a risk of severe birth defects.
How serious is the interaction between Rifampicin and Thalidomide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not depend on hormonal contraceptives; use a non-hormonal highly effective method such as a copper IUD plus a barrier method during and for several weeks after rifampicin.
What other medicines interact with Thalidomide?
MediHelp also lists interactions of Thalidomide with, for example, Bortezomib, Carbamazepine, Griseofulvin. The full list is on the Thalidomide page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
