दवाओं की अंतःक्रिया
Griseofulvin + Thalidomide
गंभीरता: गंभीर
Griseofulvin and Thalidomide: major interaction.
अंतिम अपडेट
केवल स्वास्थ्य पेशेवरों के लिए — मात्र संदर्भ हेतु। यह पृष्ठ संक्षिप्त सारांश है, चिकित्सकीय सलाह नहीं है और आधिकारिक लेबल या नैदानिक निर्णय का विकल्प नहीं है। दवा लिखने या देने से पहले हमेशा जाँच करें।
इस पृष्ठ की नैदानिक सामग्री केवल अंग्रेज़ी में उपलब्ध है।
सारांश
Griseofulvin induces hepatic enzymes and can lower hormonal contraceptive exposure, which matters because thalidomide is a potent teratogen requiring highly reliable contraception. The interaction is with the contraceptive rather than with thalidomide itself.
इस इंटरैक्शन का सरल भाषा में अर्थ
Griseofulvin and Thalidomide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Griseofulvin belongs to Anti Fungals; Thalidomide belongs to Miscellaneous.
ऐसा क्यों होता है
Enzyme induction by griseofulvin accelerates contraceptive hormone metabolism, reducing contraceptive efficacy.
क्या करें
In women of childbearing potential, do not rely on hormonal contraception alone during and for a period after griseofulvin; use an additional barrier method or a non-hormonal highly effective method such as an IUD.
फार्मासिस्ट से क्या पूछें
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ सदस्यों के लिए
पूरा पेज खोलें
Griseofulvin और Thalidomide की पूरी प्रबंधन सलाह, अतिरिक्त नोट्स, साक्ष्य का विवरण और पूरे पर्चे का इंटरैक्शन चेकर खोलने के लिए खाता बनाएँ और Pro+ ट्रायल शुरू करें।
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
वेब पर Pro+ को 7 दिन मुफ़्त आज़माएँ। कार्ड की ज़रूरत नहीं।
Thalidomide के अन्य इंटरैक्शन
- Bortezomib + Thalidomide गंभीर
- Carbamazepine + Thalidomide गंभीर
- Modafinil + Thalidomide गंभीर
- Nivolumab + Thalidomide गंभीर
- Phenytoin + Thalidomide गंभीर
- Rifabutin + Thalidomide गंभीर
Griseofulvin के अन्य इंटरैक्शन
अक्सर पूछे जाने वाले प्रश्न
Can I take Griseofulvin with Thalidomide?
MediHelp rates the interaction as major. Griseofulvin and Thalidomide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Griseofulvin induces hepatic enzymes and can lower hormonal contraceptive exposure, which matters because thalidomide is a potent teratogen requiring highly reliable contraception. The interaction is with the contraceptive rather than with thalidomide itself.
How serious is the interaction between Griseofulvin and Thalidomide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: In women of childbearing potential, do not rely on hormonal contraception alone during and for a period after griseofulvin; use an additional barrier method or a non-hormonal highly effective method such as an IUD.
What other medicines interact with Thalidomide?
MediHelp also lists interactions of Thalidomide with, for example, Bortezomib, Carbamazepine, Modafinil. The full list is on the Thalidomide page.
MediHelp ऐप में पूर्ण मोनोग्राफ़, खुराक और इंटरैक्शन चेकर
MediHelp ऐप में पूरा संदर्भ खोलें, कई दवाओं की अंतःक्रियाएँ जाँचें और खुराक टूल इस्तेमाल करें।
