Riferimento farmaci
Deucravacitinib
Deucravacitinib is a medicine in the class miscellaneous. It is used for plaque psoriasis.
- Classe del farmaco: Miscellaneous
- Indicato per: plaque psoriasis
Ultimo aggiornamento Fonti: US FDA label
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In breve
- Classe del farmaco
- Miscellaneous
- Codice ATC
- L04AF07
- Forme farmaceutiche comuni
- compressa
- Dosaggi comuni
- 6 mg
- Nomi commerciali
- 2
- Paesi e mercati
- 2
Per cosa si usa
Come agisce
Allosteric inhibitor of tyrosine kinase 2 (TYK2); binds the regulatory domain, stabilizing an inhibitory interaction with the catalytic domain and inhibiting receptor-mediated TYK2 activation and downstream STAT activation.
Dose abituale nell'adulto (sintesi del foglio illustrativo)
Plaque psoriasis and psoriatic arthritis: 6 mg orally once daily, with or without food
Gravidanza e allattamento
- Gravidanza
- Unknown Case reports are too few to assess risk; no embryo-fetal effects in rats and rabbits at doses at least 72 times the maximum human dose. Use only if the benefit justifies the risk.
- Allattamento
- Unknown No human milk data; it is present in rat milk. US label: weigh breastfeeding against the mother's need. No guidance supports routine use; an alternative with more data may be preferred.
Effetti indesiderati segnalati
- Upper respiratory infections
- Blood creatine phosphokinase increased
- Herpes simplex
- Mouth ulcers
- Folliculitis
- Acne
Controindicazioni
- History of hypersensitivity reaction to deucravacitinib or any excipients.
Chi deve prestare attenzione
- Hypersensitivity reactions such as angioedema have been reported; discontinue if clinically significant reaction occurs.
- May increase risk of infections; avoid in active or serious infection; herpes virus reactivation reported; consider hepatitis screening.
- Evaluate for latent and active TB before starting; do not give to patients with active TB.
Informare il farmacista o il medico di gravidanza o allattamento, malattie renali o epatiche, allergie e di ogni altro farmaco o integratore assunto.
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- Renal and hepatic dose adjustments
- Dosing in older adults
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- Pharmacokinetics
- Patient counselling points
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Letture rapide correlate
Domande frequenti
What is Deucravacitinib used for?
Deucravacitinib is a medicine in the class miscellaneous. It is used for Plaque psoriasis, Psoriatic arthritis.
What side effects have been reported with Deucravacitinib?
Upper respiratory infections, Blood creatine phosphokinase increased, Herpes simplex, Mouth ulcers, Folliculitis, Acne.
Can Deucravacitinib be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Case reports are too few to assess risk; no embryo-fetal effects in rats and rabbits at doses at least 72 times the maximum human dose. Use only if the benefit justifies the risk. Breastfeeding: Unknown. No human milk data; it is present in rat milk. US label: weigh breastfeeding against the mother's need. No guidance supports routine use; an alternative with more data may be preferred.
What does Deucravacitinib interact with?
MediHelp does not list a checked interaction for Deucravacitinib yet. Always tell your pharmacist about every medicine you take.
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