Riferimento farmaci
Dexlansoprazole
Dexlansoprazole is a medicine in the class gastrointestinal tract. It is used for gerd.
- Classe del farmaco: Gastrointestinal Tract
- Indicato per: gerd
Ultimo aggiornamento
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In breve
- Classe del farmaco
- Gastrointestinal Tract
- Forme farmaceutiche comuni
- capsula
- Dosaggi comuni
- 60 mg, 30 mg
- Interazioni note
- 116 (Controindicata: 2 · Maggiore: 18 · Moderata: 46 · Minore: 50)
- Nomi commerciali
- 22
- Paesi e mercati
- 4
Per cosa si usa
Come agisce
R-enantiomer of lansoprazole; PPI; binds to H+/K+-exchanging ATPase (proton pump) in gastric parietal cells, resulting in blockage of acid secretion, Dual release formulation, Relative Potency: not available.
Dose abituale nell'adulto (sintesi del foglio illustrativo)
General dosing: 30-60 mg orally every day for up to 8 weeks.
Come si assume di solito
Proton pump inhibitors are usually taken by mouth once a day, often before a meal, for a course whose length depends on the reason for treatment.
Gravidanza e allattamento
- Gravidanza
- Safe No human studies, but data for lansoprazole, of which it is an enantiomer, show no harm in pregnancy. Acceptable when a PPI is needed; omeprazole has the most pregnancy data.
- Allattamento
- Safe No milk data. LactMed: as lansoprazole has been used safely in newborns, the amount in milk is unlikely to harm the infant. Acceptable.
Effetti indesiderati segnalati
- Vomiting
- Diarrhea
- Nausea
- Abdominal pain
- URI
Controindicazioni
- Hypersensitivity reactions, including anaphylaxis and acute interstitial nephritis reported
- PPIs are contraindicated with rilpivirine-containing products
Chi deve prestare attenzione
- Proton pump inhibitors (PPIs) are possibly associated with increased incidence of Clostridium difficile-associated diarrhea (CDAD).
- PPI therapy may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist, particularly with prolonged (>1 yr), high-dose therapy.
- Daily long-term use (e.g., longer than 3 years) may lead to malabsorption or a deficiency of cyanocobalamin.
People taking proton pump inhibitors for a long time should have the need for treatment reviewed, because long-term use is linked to low magnesium, vitamin B12 deficiency, bone fractures and gut infections. Tell your pharmacist about all other medicines, since some interact.
Informare il farmacista o il medico di gravidanza o allattamento, malattie renali o epatiche, allergie e di ogni altro farmaco o integratore assunto.
Interazioni principali (116)
- Dexlansoprazole + Mavacamten Contraindicated
- Dexlansoprazole + Rilpivirine Contraindicated
- Acalabrutinib + Dexlansoprazole Major
- Atazanavir + Dexlansoprazole Major
- Dacomitinib + Dexlansoprazole Major
- Dasatinib + Dexlansoprazole Major
- Dexlansoprazole + Erlotinib Major
- Dexlansoprazole + Gefitinib Major
- Dexlansoprazole + Infigratinib Major
- Dexlansoprazole + Itraconazole Major
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- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Pharmacokinetics
- Patient counselling points
- Food interactions
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Altri farmaci della stessa classe
Domande frequenti
What is Dexlansoprazole used for?
Dexlansoprazole is a medicine in the class gastrointestinal tract. It is used for GERD, Peptic ulcer.
What side effects have been reported with Dexlansoprazole?
Vomiting, Diarrhea, Nausea, Abdominal pain, URI.
Can Dexlansoprazole be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. No human studies, but data for lansoprazole, of which it is an enantiomer, show no harm in pregnancy. Acceptable when a PPI is needed; omeprazole has the most pregnancy data. Breastfeeding: Safe. No milk data. LactMed: as lansoprazole has been used safely in newborns, the amount in milk is unlikely to harm the infant. Acceptable.
What does Dexlansoprazole interact with?
MediHelp lists 116 known interactions for Dexlansoprazole. Contraindicated: 2 · Major: 18 · Moderate: 46 · Minor: 50. The most serious include Mavacamten, Rilpivirine, Acalabrutinib.
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