Riferimento farmaci
Olsalazine
Olsalazine is a medicine in the class gastrointestinal tract. It is used for ulcerative colitis.
- Classe del farmaco: Gastrointestinal Tract
- Indicato per: ulcerative colitis
Ultimo aggiornamento
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In breve
- Classe del farmaco
- Gastrointestinal Tract
- Forme farmaceutiche comuni
- capsula
- Dosaggi comuni
- 250 mg
- Interazioni note
- 1 (Minore: 1)
- Nomi commerciali
- 3
- Paesi e mercati
- 3
Per cosa si usa
Come agisce
Converted to 5-aminosalicylic acid (mesalamine) by gastrointestinal flora which is thought to be the therapeutically active component; works topically rather than systemically.
Dose abituale nell'adulto (sintesi del foglio illustrativo)
Ulcerative Colitis Maintenance: 1g PO qDay in 2 divided doses, Take with food.
Gravidanza e allattamento
- Gravidanza
- Safe It releases mesalamine (5-ASA); meta-analyses and cohort studies of mesalamine show no reliable link with birth defects or miscarriage. Rats had developmental effects at 5 to 20 times the human dose. Active ulcerative colitis itself raises pregnancy risks, so continue when needed.
- Allattamento
- Safe Little olsalazine passes into milk, but mesalamine metabolites do (mesalamine relative infant dose 0.1% or less). A few infants had diarrhoea. LactMed: not a reason to stop breastfeeding; watch the infant for diarrhoea. US label: weigh benefits.
Effetti indesiderati segnalati
- Headache
- Diarrhea
- Abdominal pain
- Nausea/vomiting
Controindicazioni
- Patients with known or suspected hypersensitivity to salicylates, aminosalicylates or their metabolites, or excipients
Chi deve prestare attenzione
- Patients with pre-existing skin conditions such as atopic dermatitis and atopic eczema have reported more severe photosensitivity reactions when receiving therapy.
- Cases of nephrolithiasis have been reported with use of mesalamine; active moiety in drug, including stones with 100% mesalamine content.
- advise patients to avoid sun exposure, wear protective clothing, and use a broad-spectrum sunscreen when outdoors
Informare il farmacista o il medico di gravidanza o allattamento, malattie renali o epatiche, allergie e di ogni altro farmaco o integratore assunto.
Interazioni principali (1)
- Olsalazine + Warfarin Minor
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- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Pharmacokinetics
- Patient counselling points
- Food interactions
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Altri farmaci della stessa classe
Domande frequenti
What is Olsalazine used for?
Olsalazine is a medicine in the class gastrointestinal tract. It is used for Ulcerative colitis.
What side effects have been reported with Olsalazine?
Headache, Diarrhea, Abdominal pain, Nausea/vomiting.
Can Olsalazine be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. It releases mesalamine (5-ASA); meta-analyses and cohort studies of mesalamine show no reliable link with birth defects or miscarriage. Rats had developmental effects at 5 to 20 times the human dose. Active ulcerative colitis itself raises pregnancy risks, so continue when needed. Breastfeeding: Safe. Little olsalazine passes into milk, but mesalamine metabolites do (mesalamine relative infant dose 0.1% or less). A few infants had diarrhoea. LactMed: not a reason to stop breastfeeding; watch the infant for diarrhoea. US label: weigh benefits.
What does Olsalazine interact with?
MediHelp lists 1 known interactions for Olsalazine. Minor: 1. The most serious include Warfarin.
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