Riferimento farmaci
Sulfinpyrazone
Sulfinpyrazone is a medicine in the class genitourinary. It is used for gout.
- Classe del farmaco: Genitourinary
- Indicato per: gout
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In breve
- Classe del farmaco
- Genitourinary
- Forme farmaceutiche comuni
- compressa, capsula
- Dosaggi comuni
- 100 mg, 200 mg
- Nomi commerciali
- 2
- Paesi e mercati
- 1
Per cosa si usa
Come agisce
Sulfinpyrazone competitively inhibit the urate anion transporter (URAT1) responsible for reabsorption of uric acid in the proximal tubule. it increase urate excretion in urine and reduce the concentration in plasma.
Dose abituale nell'adulto (sintesi del foglio illustrativo)
200 to 400 mg orally given in 2 equally divided doses, with meals or milk, gradually increasing when necessary to full maintenance dosage in 1 week.
Gravidanza e allattamento
- Gravidanza
- Unknown Discontinued uricosuric for gout. No human pregnancy data; not teratogenic in animals. It inhibits platelet function, so bleeding around delivery is possible. UK label: use with caution, weighing risk against benefit. Uric-acid-lowering drugs are usually stopped until after pregnancy.
- Allattamento
- Unknown Not known if it passes into milk; no LactMed record. UK label: mothers should refrain from taking it, for safety reasons (no data). A uricosuric with antiplatelet action; no infant data. Avoid while breastfeeding; prefer a better-studied option chosen with the prescriber.
Effetti indesiderati segnalati
- Nausea
- Difficulty breathing
- Heartburn
- Upset Stomach
Chi deve prestare attenzione
- Avoid administering sulfinpyrazone to patients with active peptic ulcer or symptoms of GI inflammation or ulceration or patients with blood dyscrasias.
Informare il farmacista o il medico di gravidanza o allattamento, malattie renali o epatiche, allergie e di ogni altro farmaco o integratore assunto.
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- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Patient counselling points
- Food interactions
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Domande frequenti
What is Sulfinpyrazone used for?
Sulfinpyrazone is a medicine in the class genitourinary. It is used for Gout, Gouty arthritis.
What side effects have been reported with Sulfinpyrazone?
Nausea, Difficulty breathing, Heartburn, Upset Stomach.
Can Sulfinpyrazone be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Discontinued uricosuric for gout. No human pregnancy data; not teratogenic in animals. It inhibits platelet function, so bleeding around delivery is possible. UK label: use with caution, weighing risk against benefit. Uric-acid-lowering drugs are usually stopped until after pregnancy. Breastfeeding: Unknown. Not known if it passes into milk; no LactMed record. UK label: mothers should refrain from taking it, for safety reasons (no data). A uricosuric with antiplatelet action; no infant data. Avoid while breastfeeding; prefer a better-studied option chosen with the prescriber.
What does Sulfinpyrazone interact with?
MediHelp does not list a checked interaction for Sulfinpyrazone yet. Always tell your pharmacist about every medicine you take.
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