Riferimento farmaci
Thiopental
Thiopental is a medicine in the class central nervous system. It is used for anesthesia.
- Classe del farmaco: Central Nervous System
- Indicato per: anesthesia
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In breve
- Classe del farmaco
- Central Nervous System
- Forme farmaceutiche comuni
- iniezione
- Dosaggi comuni
- 1 g, 0.5 g, 500 mg
- Nomi commerciali
- 9
- Paesi e mercati
- 2
Per cosa si usa
Come agisce
Thiopental is a barbiturate used to induce general anesthesia, treat convulsions, and reduce intracranial pressure.
Dose abituale nell'adulto (sintesi del foglio illustrativo)
A normal adult dose for induction of anaesthesia is 4-6 mg/kg body weight
Gravidanza e allattamento
- Gravidanza
- Safe FDA warns that lengthy or repeated general anaesthesia in the 3rd trimester may affect fetal brain development. UK label: can be used in pregnancy without adverse effects (long caesarean use), but only when the benefit outweighs the risk; it crosses the placenta and may depress the newborn.
- Allattamento
- Safe Very small amounts pass into milk. UK label: suspend breastfeeding for at least 12 hours or express before induction. LactMed: no waiting period is needed; breastfeed once the mother is alert. With several anaesthetics, follow the most restrictive one; watch for sleepiness.
Effetti indesiderati segnalati
- Somnolence
- Bronchospasm
- Hypotension
- Heart arrythmia
- Myocardia depression
- Delayed wakening
Chi deve prestare attenzione
- Metoclopramide and droperidol reduce the dose of thiopental sodium required to induce anaesthesia.
- Midazolam potentiates the anaesthetic effects of thiopental sodium.
- Pretreatment with probenecid has been shown to potentiate thiopental sodium anaesthesia.
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- Paediatric dosing
- Patient counselling points
- Food interactions
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Domande frequenti
What is Thiopental used for?
Thiopental is a medicine in the class central nervous system. It is used for Anesthesia.
What side effects have been reported with Thiopental?
Somnolence, Bronchospasm, Hypotension, Heart arrythmia, Myocardia depression, Delayed wakening.
Can Thiopental be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. FDA warns that lengthy or repeated general anaesthesia in the 3rd trimester may affect fetal brain development. UK label: can be used in pregnancy without adverse effects (long caesarean use), but only when the benefit outweighs the risk; it crosses the placenta and may depress the newborn. Breastfeeding: Safe. Very small amounts pass into milk. UK label: suspend breastfeeding for at least 12 hours or express before induction. LactMed: no waiting period is needed; breastfeed once the mother is alert. With several anaesthetics, follow the most restrictive one; watch for sleepiness.
What does Thiopental interact with?
MediHelp does not list a checked interaction for Thiopental yet. Always tell your pharmacist about every medicine you take.
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