Riferimento farmaci
Viloxazine
Viloxazine is a medicine in the class central nervous system. It is used for adhd.
- Classe del farmaco: Central Nervous System
- Indicato per: adhd
Ultimo aggiornamento Fonti: US FDA label
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In breve
- Classe del farmaco
- Central Nervous System
- Forme farmaceutiche comuni
- capsula
- Interazioni note
- 1 (Moderata: 1)
- Nomi commerciali
- 1
- Paesi e mercati
- 1
Per cosa si usa
Come agisce
The mechanism in ADHD is unclear; it is thought to act by inhibiting norepinephrine reuptake.
Dose abituale nell'adulto (sintesi del foglio illustrativo)
ADHD (adults): start 200 mg orally once daily; titrate in 200 mg increments weekly; maximum 600 mg once daily
Gravidanza e allattamento
- Gravidanza
- Unsafe Based on animal studies, may cause maternal harm; discontinue when pregnancy is recognized unless benefits outweigh risk. Human data are insufficient.
- Allattamento
- Unknown Viloxazine is present in breastmilk at a low level (relative infant dose about 1%). No data on effects on the infant or milk production. Weigh benefits of breastfeeding against maternal need.
Effetti indesiderati segnalati
- Somnolence
- Decreased appetite
- Fatigue
- Nausea
- Vomiting
- Insomnia
Avvertenze in evidenza
- Suicidal thoughts and behaviors: higher rates were reported in ADHD patients treated with Qelbree than with placebo. Closely monitor all patients for clinical worsening and emergence of suicidal thoughts and behaviors.
Controindicazioni
- Concomitant MAOI use, or within 14 days after stopping an MAOI (risk of hypertensive crisis).
- Concomitant sensitive CYP1A2 substrates or CYP1A2 substrates with a narrow therapeutic range.
Chi deve prestare attenzione
- Suicidal thoughts and behaviors: monitor closely, especially in the first few months and at dosage changes; consider changing therapy or discontinuing if they emerge.
- Can increase heart rate and diastolic blood pressure; assess before starting, after dose increases and periodically.
- May induce manic or mixed episodes in bipolar disorder; screen patients before starting.
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Interazioni principali (1)
- Melatonin + Viloxazine Moderate
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- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
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Domande frequenti
What is Viloxazine used for?
Viloxazine is a medicine in the class central nervous system. It is used for ADHD.
What side effects have been reported with Viloxazine?
Somnolence, Decreased appetite, Fatigue, Nausea, Vomiting, Insomnia. Serious warning: Suicidal thoughts and behaviors: higher rates were reported in ADHD patients treated with Qelbree than with placebo.
Can Viloxazine be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. Based on animal studies, may cause maternal harm; discontinue when pregnancy is recognized unless benefits outweigh risk. Human data are insufficient. Breastfeeding: Unknown. Viloxazine is present in breastmilk at a low level (relative infant dose about 1%). No data on effects on the infant or milk production. Weigh benefits of breastfeeding against maternal need.
What does Viloxazine interact with?
MediHelp lists 1 known interactions for Viloxazine. Moderate: 1. The most serious include Melatonin.
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