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Interazioni tra farmaci

Acitretin + Omadacycline

Gravità: Controindicata

Acitretin and Omadacycline: contraindicated interaction.

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Sintesi

Oral retinoids and tetracycline-class antibiotics can each cause intracranial hypertension. Using them together may increase this risk, presenting with headache, nausea and visual changes. Retinoid labeling advises against concurrent tetracycline use.

Cosa significa questa interazione in parole semplici

Acitretin and Omadacycline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Acitretin belongs to Miscellaneous; Omadacycline belongs to Anti Bacterial.

Livello di evidenza: Low

Perché avviene

Additive risk of pseudotumor cerebri; the mechanism is not established.

Cosa fare

Avoid the combination and use an antibiotic from another class. If headache or visual symptoms develop, stop treatment and evaluate for papilledema.

Cosa chiedere al farmacista

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Domande frequenti

Can I take Acitretin with Omadacycline?

MediHelp rates the interaction as contraindicated. Acitretin and Omadacycline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Oral retinoids and tetracycline-class antibiotics can each cause intracranial hypertension. Using them together may increase this risk, presenting with headache, nausea and visual changes. Retinoid labeling advises against concurrent tetracycline use.

How serious is the interaction between Acitretin and Omadacycline?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and use an antibiotic from another class. If headache or visual symptoms develop, stop treatment and evaluate for papilledema.

What other medicines interact with Acitretin?

MediHelp also lists interactions of Acitretin with, for example, Demeclocycline, Doxycycline, Ethanol. The full list is on the Acitretin page.

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