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Interazioni tra farmaci

Amantadine + Dicyclomine

Gravità: Moderata

Amantadine and Dicyclomine: moderate interaction.

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Sintesi

Both drugs have anticholinergic activity, so together they can cause dry mouth, constipation, urinary retention, blurred vision, confusion and hallucinations. Older adults and those with prostatic enlargement or glaucoma are most at risk.

Cosa significa questa interazione in parole semplici

Amantadine and Dicyclomine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Amantadine belongs to Anti Virals; Dicyclomine belongs to Respiratory.

Livello di evidenza: Moderate

Perché avviene

Additive anticholinergic pharmacodynamic effects.

Cosa fare

Monitor for anticholinergic toxicity and cognitive changes, and reduce the dose or choose an alternative if they occur, particularly in the elderly.

Cosa chiedere al farmacista

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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  • Additional notes
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Domande frequenti

Can I take Amantadine with Dicyclomine?

MediHelp rates the interaction as moderate. Amantadine and Dicyclomine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs have anticholinergic activity, so together they can cause dry mouth, constipation, urinary retention, blurred vision, confusion and hallucinations. Older adults and those with prostatic enlargement or glaucoma are most at risk.

How serious is the interaction between Amantadine and Dicyclomine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic toxicity and cognitive changes, and reduce the dose or choose an alternative if they occur, particularly in the elderly.

What other medicines interact with Dicyclomine?

MediHelp also lists interactions of Dicyclomine with, for example, Clozapine, Henbane, Imipramine. The full list is on the Dicyclomine page.

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