Riferimento farmaci
Dicyclomine
Dicyclomine is a medicine in the class respiratory. It is used for irritable bowel syndrome.
- Classe del farmaco: Respiratory
- Indicato per: irritable bowel syndrome
Ultimo aggiornamento
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In breve
- Classe del farmaco
- Respiratory
- Noto anche come
- Dicycloverine
- Forme farmaceutiche comuni
- compressa, sciroppo, iniezione
- Dosaggi comuni
- 0.2%, 10 mg, 10 mg/ml
- Interazioni note
- 117 (Maggiore: 4 · Moderata: 101 · Minore: 12)
- Nomi commerciali
- 5
- Paesi e mercati
- 2
Per cosa si usa
Come agisce
Anticholinergic/antispasmodic; no effect on acid secretion, but direct smooth muscle relaxant effects; blocks the action of ACh at parasympathetic sites in smooth muscle, secretory glands, and CNS.
Dose abituale nell'adulto (sintesi del foglio illustrativo)
Irritable Bowel Syndrome: 10-20 mg IM q6hr; not to exceed 80 mg/day IM
Gravidanza e allattamento
- Gravidanza
- Safe Studies of 1st-trimester use at up to 40 mg/day (as in older morning-sickness products) showed no rise in malformations; data at higher IBS doses are lacking. Can be used if needed.
- Allattamento
- Unsafe Passes into milk; a possible case of apnoea in a breastfed infant was reported, like reactions in infants given it directly (contraindicated under 6 months). US label and LactMed: do not use while breastfeeding.
Effetti indesiderati segnalati
- Drowsiness
- Dry mouth
- Blurred vision
- Dizziness
Controindicazioni
- Hypersensitivity to dicyclomine or any anticholinergic drugs
- Closed-angle glaucoma
- Myasthenia gravis
Chi deve prestare attenzione
- Serious respiratory reactions, CNS symptoms, and deaths reported following administration to infants.
- Contraindicated in Patients with Closed-angle glaucoma, GI obstruction, Severe ulcerative colitis, Reflux esophagitis, bladder obstruction, or Infants aged <6 months.
- Caution in benign prostatic hyperplasia, and Heat prostration can occur (fever and heat stroke due to decreased sweating).
Informare il farmacista o il medico di gravidanza o allattamento, malattie renali o epatiche, allergie e di ogni altro farmaco o integratore assunto.
Interazioni principali (117)
- Clozapine + Dicyclomine Major
- Dicyclomine + Henbane Major
- Dicyclomine + Imipramine Major
- Dicyclomine + Pramlintide Major
- Abobotulinumtoxina + Dicyclomine Moderate
- Aclidinium + Dicyclomine Moderate
- Amantadine + Dicyclomine Moderate
- Amitriptyline + Dicyclomine Moderate
- Amoxapine + Dicyclomine Moderate
- Atropine + Dicyclomine Moderate
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- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Dosing in older adults
- Pharmacokinetics
- Patient counselling points
- Food interactions
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Altri farmaci della stessa classe
Domande frequenti
What is Dicyclomine used for?
Dicyclomine is a medicine in the class respiratory. It is used for Irritable bowel syndrome.
What side effects have been reported with Dicyclomine?
Drowsiness, Dry mouth, Blurred vision, Dizziness.
Can Dicyclomine be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. Studies of 1st-trimester use at up to 40 mg/day (as in older morning-sickness products) showed no rise in malformations; data at higher IBS doses are lacking. Can be used if needed. Breastfeeding: Unsafe. Passes into milk; a possible case of apnoea in a breastfed infant was reported, like reactions in infants given it directly (contraindicated under 6 months). US label and LactMed: do not use while breastfeeding.
What does Dicyclomine interact with?
MediHelp lists 117 known interactions for Dicyclomine. Major: 4 · Moderate: 101 · Minor: 12. The most serious include Clozapine, Henbane, Imipramine.
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