Interazioni tra farmaci
Anastrozole + Bazedoxifene / conjugated estrogens
Gravità: Controindicata
Anastrozole and Bazedoxifene / conjugated estrogens: contraindicated interaction.
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Sintesi
Anastrozole lowers estrogen levels in postmenopausal women with hormone receptor-positive breast cancer, whereas conjugated estrogens supply estrogen. The therapy opposes the intended anti-estrogen effect and may reduce cancer control.
Cosa significa questa interazione in parole semplici
Anastrozole and Bazedoxifene / conjugated estrogens are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Pharmacodynamic antagonism: exogenous estrogen counteracts aromatase inhibition.
Cosa fare
Do not combine. Use non-hormonal options for vasomotor symptoms in patients on anastrozole.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Anastrozole
- Anastrozole + Bazedoxifene-conjugated estrogens Controindicata
- Anastrozole + Conjugated estrogens Controindicata
- Anastrozole + Estradiol Controindicata
- Anastrozole + Estrogens conjugated synthetic Controindicata
- Anastrozole + Estrogens esterified Controindicata
- Anastrozole + Estropipate Controindicata
Domande frequenti
Can I take Anastrozole with Bazedoxifene / conjugated estrogens?
MediHelp rates the interaction as contraindicated. Anastrozole and Bazedoxifene / conjugated estrogens are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Anastrozole lowers estrogen levels in postmenopausal women with hormone receptor-positive breast cancer, whereas conjugated estrogens supply estrogen. The therapy opposes the intended anti-estrogen effect and may reduce cancer control.
How serious is the interaction between Anastrozole and Bazedoxifene / conjugated estrogens?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine. Use non-hormonal options for vasomotor symptoms in patients on anastrozole.
What other medicines interact with Anastrozole?
MediHelp also lists interactions of Anastrozole with, for example, Bazedoxifene-conjugated estrogens, Conjugated estrogens, Estradiol. The full list is on the Anastrozole page.
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