Interazioni tra farmaci
Anidulafungin + Saccharomyces boulardii
Gravità: Moderata
Anidulafungin and Saccharomyces boulardii: moderate interaction.
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Sintesi
Anidulafungin is active against yeasts and may reduce the viability of S. boulardii, lessening the probiotic effect. Live yeast probiotics have also been associated with fungemia in critically ill or catheterized patients.
Cosa significa questa interazione in parole semplici
Anidulafungin and Saccharomyces boulardii can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Perché avviene
Pharmacodynamic antagonism: antifungal activity against the live yeast probiotic.
Cosa fare
Avoid the probiotic during systemic antifungal therapy, especially in critically ill patients or those with central lines. Resume only after antifungal treatment is completed if still needed.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Anidulafungin
- Anidulafungin + Voclosporin Minore
Domande frequenti
Can I take Anidulafungin with Saccharomyces boulardii?
MediHelp rates the interaction as moderate. Anidulafungin and Saccharomyces boulardii can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Anidulafungin is active against yeasts and may reduce the viability of S. boulardii, lessening the probiotic effect. Live yeast probiotics have also been associated with fungemia in critically ill or catheterized patients.
How serious is the interaction between Anidulafungin and Saccharomyces boulardii?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the probiotic during systemic antifungal therapy, especially in critically ill patients or those with central lines. Resume only after antifungal treatment is completed if still needed.
What other medicines interact with Anidulafungin?
MediHelp also lists interactions of Anidulafungin with, for example, Voclosporin. The full list is on the Anidulafungin page.
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