Interazioni tra farmaci
Anti-thymocyte + Measles mumps and rubella vaccine live
Gravità: Controindicata
Anti-thymocyte and Measles mumps and rubella vaccine live: contraindicated interaction.
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Sintesi
The live MMR vaccine can cause disseminated vaccine-virus infection in patients heavily immunosuppressed by anti-thymocyte globulin. Immunogenicity is also reduced.
Cosa significa questa interazione in parole semplici
Anti-thymocyte and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Impaired cell-mediated immunity permits uncontrolled replication of live attenuated viruses.
Cosa fare
Avoid live MMR vaccine during and after anti-thymocyte globulin until immune recovery is documented. If needed, vaccinate at least 4 weeks before therapy.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Anti-thymocyte
- Anti-thymocyte + Bcg vaccine live Controindicata
- Anti-thymocyte + Influenza virus vaccine quadrivalent intranasal Controindicata
- Anti-thymocyte + Measles mumps rubella and varicella vaccine live Controindicata
- Anti-thymocyte + Measles vaccine Controindicata
- Anti-thymocyte + Rotavirus oral vaccine live Controindicata
- Anti-thymocyte + Rubella vaccine Controindicata
Domande frequenti
Can I take Anti-thymocyte with Measles mumps and rubella vaccine live?
MediHelp rates the interaction as contraindicated. Anti-thymocyte and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The live MMR vaccine can cause disseminated vaccine-virus infection in patients heavily immunosuppressed by anti-thymocyte globulin. Immunogenicity is also reduced.
How serious is the interaction between Anti-thymocyte and Measles mumps and rubella vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live MMR vaccine during and after anti-thymocyte globulin until immune recovery is documented. If needed, vaccinate at least 4 weeks before therapy.
What other medicines interact with Anti-thymocyte?
MediHelp also lists interactions of Anti-thymocyte with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps rubella and varicella vaccine live. The full list is on the Anti-thymocyte page.
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