Interazioni tra farmaci
Anti-thymocyte + Measles vaccine
Gravità: Controindicata
Anti-thymocyte and Measles vaccine: contraindicated interaction.
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Sintesi
Measles vaccine is a live attenuated vaccine, and in a patient profoundly immunosuppressed by anti-thymocyte globulin the vaccine virus may replicate unchecked and cause disseminated disease. The vaccine response will also be poor.
Cosa significa questa interazione in parole semplici
Anti-thymocyte and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Impaired cell-mediated immunity permits uncontrolled replication of live attenuated virus.
Cosa fare
Do not give live measles vaccine during and for an extended period after anti-thymocyte globulin until immune recovery is confirmed. Give it at least 4 weeks before starting therapy if vaccination is needed.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Anti-thymocyte
- Anti-thymocyte + Bcg vaccine live Controindicata
- Anti-thymocyte + Influenza virus vaccine quadrivalent intranasal Controindicata
- Anti-thymocyte + Measles mumps and rubella vaccine live Controindicata
- Anti-thymocyte + Measles mumps rubella and varicella vaccine live Controindicata
- Anti-thymocyte + Rotavirus oral vaccine live Controindicata
- Anti-thymocyte + Rubella vaccine Controindicata
Domande frequenti
Can I take Anti-thymocyte with Measles vaccine?
MediHelp rates the interaction as contraindicated. Anti-thymocyte and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Measles vaccine is a live attenuated vaccine, and in a patient profoundly immunosuppressed by anti-thymocyte globulin the vaccine virus may replicate unchecked and cause disseminated disease. The vaccine response will also be poor.
How serious is the interaction between Anti-thymocyte and Measles vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live measles vaccine during and for an extended period after anti-thymocyte globulin until immune recovery is confirmed. Give it at least 4 weeks before starting therapy if vaccination is needed.
What other medicines interact with Anti-thymocyte?
MediHelp also lists interactions of Anti-thymocyte with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Anti-thymocyte page.
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