Interazioni tra farmaci
Atropine + Bethanechol
Gravità: Moderata
Atropine and Bethanechol: moderate interaction.
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Sintesi
Atropine is a competitive muscarinic antagonist and directly opposes the muscarinic agonist effects of bethanechol on the bladder, gut and other organs. Bethanechol may therefore lose its efficacy, and atropine can be used to reverse bethanechol toxicity.
Cosa significa questa interazione in parole semplici
Atropine and Bethanechol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atropine belongs to Miscellaneous; Bethanechol belongs to Gastrointestinal Tract.
Perché avviene
Pharmacodynamic antagonism at muscarinic receptors.
Cosa fare
Avoid routine co-administration because therapeutic effect is lost; if bethanechol overdose or cholinergic toxicity occurs, atropine is the appropriate antidote.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Bethanechol
- Bethanechol + Darifenacin Maggiore
- Bethanechol + Fesoterodine Maggiore
- Bethanechol + Oxybutynin Maggiore
- Bethanechol + Physostigmine Maggiore
- Amifampridine + Bethanechol Moderata
- Amitriptyline + Bethanechol Moderata
Altre interazioni di Atropine
- Atropine + Eluxadoline Maggiore
- Atropine + Henbane Maggiore
- Atropine + Pramlintide Maggiore
- Abobotulinumtoxina + Atropine Moderata
- Aclidinium + Atropine Moderata
- Amantadine + Atropine Moderata
Domande frequenti
Can I take Atropine with Bethanechol?
MediHelp rates the interaction as moderate. Atropine and Bethanechol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Atropine is a competitive muscarinic antagonist and directly opposes the muscarinic agonist effects of bethanechol on the bladder, gut and other organs. Bethanechol may therefore lose its efficacy, and atropine can be used to reverse bethanechol toxicity.
How serious is the interaction between Atropine and Bethanechol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid routine co-administration because therapeutic effect is lost; if bethanechol overdose or cholinergic toxicity occurs, atropine is the appropriate antidote.
What other medicines interact with Bethanechol?
MediHelp also lists interactions of Bethanechol with, for example, Darifenacin, Fesoterodine, Oxybutynin. The full list is on the Bethanechol page.
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