Interazioni tra farmaci
Balsalazide + Celecoxib
Gravità: Moderata
Balsalazide and Celecoxib: moderate interaction.
Ultimo aggiornamento
Per operatori sanitari — solo a scopo di riferimento. Questa pagina è una sintesi breve, non è un parere medico e non sostituisce il RCP ufficiale né il giudizio clinico. Verificare sempre prima di prescrivere o dispensare.
Il contenuto clinico di questa pagina è disponibile solo in inglese.
Sintesi
Balsalazide releases mesalamine in the colon, and celecoxib is an NSAID with renal effects. Concurrent use may add to the risk of renal impairment, especially with dehydration or pre-existing kidney disease. NSAIDs may also aggravate inflammatory bowel disease in some patients.
Cosa significa questa interazione in parole semplici
Balsalazide and Celecoxib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Balsalazide belongs to Gastrointestinal Tract; Celecoxib belongs to Musculoskeletal.
Perché avviene
Additive nephrotoxic potential from NSAID-mediated prostaglandin inhibition and rare mesalamine-related interstitial nephritis.
Cosa fare
Monitor renal function periodically and watch for worsening bowel symptoms. Avoid long-term NSAID use where an alternative analgesic is suitable.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Per gli utenti Pro+
Sblocca la pagina completa
Crei un account e avvii una prova di Pro+ per sbloccare le indicazioni complete sulla gestione di Balsalazide e Celecoxib, le note aggiuntive, il dettaglio delle evidenze e il controllo delle interazioni per un'intera prescrizione.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Provi Pro+ gratis per 14 giorni sul web. Nessuna carta.
Altre interazioni di Balsalazide
- Balsalazide + Measles mumps rubella and varicella vaccine live Maggiore
- Balsalazide + Varicella virus vaccine live Maggiore
- Aceclofenac + Balsalazide Moderata
- Balsalazide + Mesalamine Moderata
- Balsalazide + Vadadustat Moderata
- Balsalazide + Voclosporin Moderata
Altre interazioni di Celecoxib
- Celecoxib + Ketorolac Controindicata
- Celecoxib + Ketorolac intranasal Controindicata
- Aceclofenac + Celecoxib Maggiore
- Acemetacin + Celecoxib Maggiore
- Amiloride + Celecoxib Maggiore
- Apixaban + Celecoxib Maggiore
Domande frequenti
Can I take Balsalazide with Celecoxib?
MediHelp rates the interaction as moderate. Balsalazide and Celecoxib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Balsalazide releases mesalamine in the colon, and celecoxib is an NSAID with renal effects. Concurrent use may add to the risk of renal impairment, especially with dehydration or pre-existing kidney disease. NSAIDs may also aggravate inflammatory bowel disease in some patients.
How serious is the interaction between Balsalazide and Celecoxib?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function periodically and watch for worsening bowel symptoms. Avoid long-term NSAID use where an alternative analgesic is suitable.
What other medicines interact with Balsalazide?
MediHelp also lists interactions of Balsalazide with, for example, Measles mumps rubella and varicella vaccine live, Varicella virus vaccine live, Aceclofenac. The full list is on the Balsalazide page.
Monografie complete, posologie e verifica delle interazioni nell'app MediHelp
Apra il riferimento completo, verifichi le interazioni tra più farmaci e usi gli strumenti di posologia nell'app MediHelp.
