Interazioni tra farmaci
Belimumab + Measles mumps and rubella vaccine
Gravità: Maggiore
Belimumab and Measles mumps and rubella vaccine: major interaction.
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Sintesi
Belimumab is a B-cell survival inhibitor that dampens immune function, so live vaccine viruses may replicate more and the vaccine response may be reduced. Labeling advises against live vaccines with belimumab.
Cosa significa questa interazione in parole semplici
Belimumab and Measles mumps and rubella vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Belimumab belongs to Miscellaneous; Measles mumps and rubella vaccine belongs to Miscellaneous.
Perché avviene
Inhibition of BLyS reduces B-cell activity, which may blunt vaccine response and impair control of live attenuated viruses.
Cosa fare
Do not give live vaccines within the 30 days before or during belimumab therapy. Update vaccinations beforehand.
Cosa chiedere al farmacista
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Altre interazioni di Measles mumps and rubella vaccine
- Adalimumab + Measles mumps and rubella vaccine Controindicata
- Anakinra + Measles mumps and rubella vaccine Controindicata
- Antithymocyte globulin equine + Measles mumps and rubella vaccine Controindicata
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine Controindicata
- Azathioprine + Measles mumps and rubella vaccine Controindicata
- Basiliximab + Measles mumps and rubella vaccine Controindicata
Altre interazioni di Belimumab
- Abatacept + Belimumab Moderata
- Adalimumab + Belimumab Moderata
- Anakinra + Belimumab Moderata
- Anti-thymocyte + Belimumab Moderata
- Belimumab + Denosumab Moderata
- Belimumab + Fingolimod Moderata
Domande frequenti
Can I take Belimumab with Measles mumps and rubella vaccine?
MediHelp rates the interaction as major. Belimumab and Measles mumps and rubella vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Belimumab is a B-cell survival inhibitor that dampens immune function, so live vaccine viruses may replicate more and the vaccine response may be reduced. Labeling advises against live vaccines with belimumab.
How serious is the interaction between Belimumab and Measles mumps and rubella vaccine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live vaccines within the 30 days before or during belimumab therapy. Update vaccinations beforehand.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
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