Vai al contenuto

Interazioni tra farmaci

Benazepril + Hydrochlorothiazide-lisinopril

Gravità: Maggiore

Benazepril and Hydrochlorothiazide-lisinopril: major interaction.

Ultimo aggiornamento

Per operatori sanitari — solo a scopo di riferimento. Questa pagina è una sintesi breve, non è un parere medico e non sostituisce il RCP ufficiale né il giudizio clinico. Verificare sempre prima di prescrivere o dispensare.

Il contenuto clinico di questa pagina è disponibile solo in inglese.

Sintesi

Benazepril duplicates the ACE inhibitor lisinopril, giving no added benefit and increasing the risk of hypotension, hyperkalemia and acute kidney injury. Dual ACE inhibitor therapy should not be used.

Cosa significa questa interazione in parole semplici

Benazepril and Hydrochlorothiazide-lisinopril can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Benazepril belongs to Cardiovascular; Hydrochlorothiazide-lisinopril belongs to Cardiovascular.

Livello di evidenza: High

Perché avviene

Therapeutic duplication causing excessive ACE inhibition and reduced angiotensin II and aldosterone.

Cosa fare

Avoid combining two ACE inhibitors and discontinue one. Monitor blood pressure, creatinine and potassium after the change.

Cosa chiedere al farmacista

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Per gli utenti Pro+

Sblocca la pagina completa

Crei un account e avvii una prova di Pro+ per sbloccare le indicazioni complete sulla gestione di Benazepril e Hydrochlorothiazide-lisinopril, le note aggiuntive, il dettaglio delle evidenze e il controllo delle interazioni per un'intera prescrizione.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Provi Pro+ gratis per 14 giorni sul web. Nessuna carta.

Domande frequenti

Can I take Benazepril with Hydrochlorothiazide-lisinopril?

MediHelp rates the interaction as major. Benazepril and Hydrochlorothiazide-lisinopril can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Benazepril duplicates the ACE inhibitor lisinopril, giving no added benefit and increasing the risk of hypotension, hyperkalemia and acute kidney injury. Dual ACE inhibitor therapy should not be used.

How serious is the interaction between Benazepril and Hydrochlorothiazide-lisinopril?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining two ACE inhibitors and discontinue one. Monitor blood pressure, creatinine and potassium after the change.

What other medicines interact with Hydrochlorothiazide-lisinopril?

MediHelp also lists interactions of Hydrochlorothiazide-lisinopril with, for example, Dofetilide, Sacubitril / valsartan, Amifostine. The full list is on the Hydrochlorothiazide-lisinopril page.

Monografie complete, posologie e verifica delle interazioni nell'app MediHelp

Apra il riferimento completo, verifichi le interazioni tra più farmaci e usi gli strumenti di posologia nell'app MediHelp.

Sfoglia dalla A alla Z · Interazioni tra farmaci

Scarica l'app Accedi