Interazioni tra farmaci
Calcium + Oxytetracycline
Gravità: Moderata
Calcium and Oxytetracycline: moderate interaction.
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Sintesi
Oral calcium markedly reduces the absorption of oxytetracycline, which can lead to subtherapeutic antibiotic levels and treatment failure. Dairy-type calcium sources and supplements both contribute.
Cosa significa questa interazione in parole semplici
Calcium and Oxytetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Calcium belongs to Gastrointestinal Tract; Oxytetracycline belongs to Anti Bacterial.
Perché avviene
Calcium cations chelate oxytetracycline in the gut, forming non-absorbable complexes.
Cosa fare
Take oxytetracycline at least 2 hours before or 4 hours after calcium products. Consider a different antibiotic if calcium cannot be withheld.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Calcium
- Calcium + Ceftriaxone Controindicata
- Acalabrutinib + Calcium Moderata
- Alendronate + Calcium Moderata
- Atazanavir + Calcium Moderata
- Baloxavir marboxil + Calcium Moderata
- Bendroflumethiazide + Calcium Moderata
Altre interazioni di Oxytetracycline
- Isotretinoin + Oxytetracycline Controindicata
- Aluminum hydroxide + Oxytetracycline Moderata
- Ampicillin-sulbactam + Oxytetracycline Moderata
- Ampicillin + Oxytetracycline Moderata
- Atracurium + Oxytetracycline Moderata
- Bismuth subsalicylate + Oxytetracycline Moderata
Domande frequenti
Can I take Calcium with Oxytetracycline?
MediHelp rates the interaction as moderate. Calcium and Oxytetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral calcium markedly reduces the absorption of oxytetracycline, which can lead to subtherapeutic antibiotic levels and treatment failure. Dairy-type calcium sources and supplements both contribute.
How serious is the interaction between Calcium and Oxytetracycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take oxytetracycline at least 2 hours before or 4 hours after calcium products. Consider a different antibiotic if calcium cannot be withheld.
What other medicines interact with Calcium?
MediHelp also lists interactions of Calcium with, for example, Ceftriaxone, Acalabrutinib, Alendronate. The full list is on the Calcium page.
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